Dott. Luigi Angelo Vaira


Sono un chirurgo maxillo-facciale, ricercatore universitario e dirigente medico presso l’Unità Operativa Complessa di Chirurgia Maxillo-Facciale dell’AOU di Sassari. La mia attività si sviluppa tra chirurgia, ricerca scientifica, didattica universitaria e innovazione tecnologica applicata alla medicina.

Attualmente sono ricercatore universitario a tempo determinato in Chirurgia Maxillo-Facciale presso il Dipartimento di Medicina, Chirurgia e Farmacia dell’Università degli Studi di Sassari. Dal 2025 coordino il Centro di Simulazione Medica “SimulMedica” dell’Ateneo e il Comitato Comunicazione del Dipartimento di Medicina, Chirurgia e Farmacia, contribuendo allo sviluppo di nuovi modelli di formazione medica, comunicazione scientifica e divulgazione sanitaria.

Mi sono laureato in Medicina e Chirurgia con lode nel 2011, mi sono specializzato in Chirurgia Maxillo-Facciale presso l’Università degli Studi di Napoli nel 2017 e ho conseguito il Dottorato di Ricerca in Scienze Biomediche – Neuroscienze nel 2024. Nel 2025 ho ottenuto l’Abilitazione Scientifica Nazionale a Professore di I fascia per il settore di Chirurgia Maxillo-Facciale e l’abilitazione a Professore di II fascia per il settore di Otorinolaringoiatria.

La mia attività clinico-chirurgica comprende i principali ambiti della chirurgia maxillo-facciale: traumatologia cranio-facciale, chirurgia ortognatica, chirurgia orale complessa, implantologia avanzata, ricostruzioni oncologiche e trattamento delle gravi atrofie dei mascellari. Nel tempo ho sviluppato un particolare interesse per i disordini dell’articolazione temporo-mandibolare, la patologia orale, la chirurgia estetica del volto e le riabilitazioni implantari complesse, anche attraverso l’impiego di tecnologie digitali e dispositivi custom-made.

Accanto all’attività ospedaliera e universitaria, collaboro come consulente specialistico con oltre 40 studi odontoiatrici e medici, occupandomi della pianificazione e del trattamento di casi complessi di chirurgia orale, implantologia avanzata, chirurgia dei mascellari e patologia del distretto testa-collo.

La ricerca scientifica è una parte centrale del mio percorso professionale. Sono autore di oltre 300 pubblicazioni indicizzate, con più di 6.000 citazioni e un H-index Scopus di 40. Dal 2021 il mio nome è incluso nelle classifiche internazionali della Stanford University relative al 2% dei ricercatori più produttivi e citati al mondo.

I miei principali filoni di ricerca riguardano l’applicazione dell’intelligenza artificiale in chirurgia maxillo-facciale, la chirurgia computer-assistita, la pianificazione digitale, le tecniche rigenerative dei mascellari, i disturbi chemosensoriali post-COVID-19 e le nuove strategie ricostruttive in ambito cranio-maxillo-facciale. Coordino e partecipo a numerosi progetti multicentrici nazionali e internazionali, con l’obiettivo di integrare ricerca, innovazione e pratica clinica.

Sono titolare di insegnamenti di Chirurgia Orale, Chirurgia Maxillo-Facciale e Traumatologia Maxillo-Facciale in corsi di laurea, scuole di specializzazione e percorsi formativi universitari. Partecipo regolarmente come relatore invitato a congressi, corsi e meeting nazionali e internazionali, portando contributi su chirurgia maxillo-facciale, implantologia avanzata, tecnologie digitali, simulazione medica e innovazione in ambito sanitario.

La mia visione della chirurgia maxillo-facciale si fonda sull’integrazione tra competenza clinica, precisione chirurgica, ricerca scientifica e attenzione alla persona. Ogni trattamento viene affrontato come un percorso personalizzato, costruito sulle esigenze funzionali, estetiche e umane del paziente, con l’obiettivo di ottenere risultati efficaci, sicuri e rispettosi dell’identità individuale.


  • Esperienza formativa e lavorativa

    Luglio 2017 - Presente

    Chirurgo Maxillo-Facciale, attività libero professionale e di consulenza presso studi odontoiatrici.


    Aprile 2018 - Presente

    Dirigente medico - U.O.C. Chirurgia Maxillo-Facciale - A.O.U. Sassari


    Agosto 2017 - Aprile 2018

    Borsa di ricerca in “Valutazione dell’outcome funzionale delle ricostruzioni post-resettive del cavo orale e dell’orofaringe” presso l'Università degli Studi di Sassari


    Luglio 2012 - Luglio 2017

    Scuola di specializzazione - U.O.C. Chirurgia Maxillo-Facciale - A.O.U Federico II di Napoli


    Settembre 2009 - Luglio 2012

    Internato presso l'U.O.C. di Chirurgia Maxillo-Facciale dell'A.O.U. di Sassari.


    Settembre 2007

    Periodo di frequenza presso l'Head and Neck Surgery Unit - Universitade de Marilia, SP, Brasil.



  • Pubblicazioni scientifiche

    1. Vaira LA, Soma D, Meloni SM, Dell’aversana Orabona G, Piombino P, De Riu G. Vertiginous crisis following temporomandibular joint arthrocentesis: a case report. Oral Maxillofac Surg. 2017;21(1):79-81. (First author, Corresponding author).


    2. Vaira LA, Massarelli O, Meloni SM, Dell’aversana Orabona G, Piombino P, De Riu G. Alveolar nerve impairment following bilateral sagittal split ramus osteotomy and genioplasty. J Maxillofac Surg Med Pathol. 2017;29(3):203-9. (First author, Correspondibg author).


    3. Friscia M, Sbordone C, Petrocelli M, Vaira LA, Attanasi F, Cassandro FM, Paternoster M, Iaconetta G, Califano L. Complications after orthognathic surgery: our experience on 423 cases. Oral Maxillofac Surg. 2017;21:171-7. (Corresponding author).


    4. Vaira LA, Massarelli O, Deiana A, Vacca G, Dell’aversana Orabona G, Piombino P, De Riu G. The mandibular condyle as uncommon metastatic site of neuroendocrine carcinoma: case report and review of literature. J Oral Maxillofac Surg Med Pathol. 2017;29(4):314-20. (First author, Corresponding, author).


    5. Bonavolontà P, Dell’aversana Orabona G, Abbate V, Vaira LA, Lo Faro C, Petrocelli M, Attanasi F, De Riu G, Iaconetta G, Califano L. The epidemiological analysis of maxillofacial fractures in Italy: the experience of a single tertiary center on 1720 patients. J Craniomaxillofac Surg. 2017;45:1319-26. (Corresponding author).


    6. Massarelli O, Vaira LA, De Riu G. Islanded facial artery musculomucosal flap for tongue reconstruction. Int J Oral Maxillofac Surg. 2017;46(8):1060-1. (Corresponding author).


    7. Vaira LA, Massarelli O, Gobbi R, Soma D, Dell’aversana Orabona G, Piombino P, De Riu G. Evaluation of discriminative sensibility recovery in patients with buccinator myomucosal flap oral cavity reconstructions. Eur J Plast Surg. 2017;40:427-34. (First author; Corresponding author).


    8. Massarelli O, Vaira LA, Biglio A, Gobbi R, Piombino P, De Riu G. Rational and simplified nomenclature for buccinator myomucosal flaps. Oral Maxillofac Surg. 2017;21(4):453-9. (Co-first author, Corresponding author).


    9. Sbordone S, Barca I, Petrocelli M, Dell’aversana Orabona G, Vaira LA, Colangeli W, Cristofaro MG, Giudice M, Giudice A, Cassandro FM, Attanasi F, Iaconetta G, Califano L. The influence of socioeconomic factors on the epidemiology of maxillofacial fractures in southern Italy. J Craniofac Surg. 2018;29(8):2119-23.


    10. De Riu G, Virdis PI, Meloni SM, Lumbau A, Vaira LA. Accuracy of computer-assisted orthognathic surgery. J Cranio-Maxillofac Surg. 2018;46(2):293-8. (Last author, Corresponding author).


    11. Massarelli O, Vaira LA, Biglio A, Gobbi R, Dell’aversana Orabona G, De Riu G. Soft palate functional reconstruction with buccinator myomucosal island flaps. Int J Oral Maxillofac Surg. 2018;47(3):316-23. (Co-first author, Corresponding author).


    12. Massarelli O, Vaira LA, Biglio A, Gobbi R, Dell’aversana Orabona G, De Riu G. Sensory recovery of buccinator myomucosal flap oral cavity reconstructions. Head Neck. 2018;40(3):467-74. (Co-first author, Corresponding author).


    13. Vaira LA, Massarelli O, Deiana G, Meloni SM, Dell’aversana Orabona G, Piombino P, De Riu G. Aesthetic and functional evaluation of total nasal reconstructions. Indian J Otolaryngol Head Neck Surg. 2018;70(1):71-8. (First author, Corresponding author).


    14. Massarelli O, Vaira LA, De Riu G. Comment on: Facial artery myomucosal flap, pedicled solely on the facial artery: experimental design study on survival. J Craniofac Surg. 2018;29(3):809. (Corresponding author).


    15. Massarelli O, Vaira LA, Gobbi R, Dell’aversana Orabona G, De Riu G. Reconstruction of full-thickness cheek defect with chimeric facial artery free flap: a case report. Microsurgery. 2018;38(4):427-31. (Co-first author, Corresponding author).


    16. Romano A, Lo Faro C, Salzano G, Dell’aversana Orabona G, Petrocelli M, Corvino R, Vaira LA, Iaconetta G, Califano L. Synovial chondromatosis of temporomandibular joint spreading into the cranial space. J Oral Maxillofac Surg Med Pathol. 2018;30(3):267-71.


    17. Vaira LA, Massarelli O, Gobbi R, Biglio A, De Riu G. Tactile recovery assessment with shortened Semmes-Weinstein monofilaments in patients with buccinator myomucosal flap oral cavity reconstructions. Oral Maxillofac Surg. 2018;22(2):151-6. (First author, Corresponding author).


    18. Vaira LA, Raho MT, Soma D, Salzano G, Dell’aversana Orabona G, Piombino P, De Riu G. Complications and post-operative sequelae of temporomandibular joint arthrocentesis. Cranio. 2018;36(4):264-7. (First author, Corresponding author).


    19. De Riu G, Vaira LA, Carta E, Meloni SM, Sembronio S, Robiony M. Bone marrow nucleated cell concentrate autograft in temporomandibular joint degenerative disorders: 1-year results of a randomized clinical trial. J Cranio-maxillofac Surg. 2019;47(11):1728-38. (Corresponiding Author)


    20. Vaira LA, Salzano G, Deiana G, De Riu G. Anosmia and ageusia: common findings in COVID-19 patients. Laryngoscope. 2020;130(7):1787. (First author, Corresponding author).


    21. Vaira LA, Salzano G, Fois AG, Piombino P, De Riu G. Potential pathogenesis of ageusia and anosmia in COVID-19 patients. Int Forum Allergy Rhinol. 2020;10(9):1103-1104. (First author, Corresponding author).


    22. Vaira LA, Salzano G, De Riu G. The importance of olfactory and gustatory disorders as early symptoms of coronavirus disease (COVID-19). Br J Oral Maxillofac Surg. 2020;58(5):615-616. (First author, Corresponding author).


    23. Vaira LA, Deiana G, Fois AG, Pirina P, Madeddu G, De Vito A, Babudieri S, Petrocelli M, Serra A, Bussu F, Ligas E, Salzano G, De Riu G. Objective evaluation of anosmia and ageusia in COVID-19 patients: single-center experience on 72 cases. Head Neck. 2020;42(6):1252-1258. (First author, Corresponding author).


    24. Vaira LA, Salzano G, Petrocelli M, Deiana G, Salzano FA, De Riu G. Validation of a self-administered olfactory and gustatory test for the remotely evaluation of COVID-19 patients in home quarantine. Head Neck. 2020;42(7):1570-1576. (First author, Corresponding author).


    25. Vaira LA, Hopkins C, Salzano G, Petrocelli M, Melis A, Cucurullo M, Ferrari M, Galgiardini L, Pipolo C, Deiana G, Fiore V, De Vito A, Turra N, Canu S, Maglio A, Serra A, Bussu F, Madeddu G, Babudieri S, Fois AG, Pirina P, Salzano FA, De Riu P, Biglioli F, De Riu G. Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenter-study. Head Neck. 2020;42(7):1560-1569. (First author, Corresponding author).


    26. Vaira LA, Hopkins C, Petrocelli M, Lechien JR, Chiesa-Estomba CM, Salzano G, Cucurullo M, Salzano FA, Saussez S, Boscolo-Rizzo P, Biglioli F, De Riu G. Smell and taste recovery in coronavirus disease 2019 patients: a 60-day objective and prospective study. J Laryngol Otol. 2020;134(8):703-709. (First author, Corresponding author).


    27. Vaira LA, Hopkins C, Petrocelli M, Lechien JR, Soma D, Giovanditto F, Rizzo D, Salzano G, Piombino P, Saussez S, De Riu G. Do olfactory and gustatory psycophysical scores have prognostic value in COVID-19 patients? A prospective study of 106 patients. J Otolaryngol Head Neck Surg. 2020;49(1):56. (First author, Corresponding author).


    28. Maglitto F, Salzano G, Vaira LA, Salzano FA, De Riu G. Anosmia: a COVID-19 symptom that must be investigated by rhinoplasty surgeons. Eur J Plast Surg.  2020;43(6):865-866


    29. Vaira LA, Salzano G, Deiana G, De Riu G. In response to isolated anosmia and ageusia in COVID-19 with spontaneous recovery. Laryngoscope. 2020;130(9):E503. (First author, Corresponding author).


    30. Vaira LA, Salzano G, De Riu G. Reader response: Miller Fisher syndrome and polyneuritis cranialis in COVID-19. Neurology. 2020;95(8):368-369. (First author, Corresponding author).


    31. Vaira LA, Lechien JR, Salzano G, Salzano FA, Maglitto F, Saussez S, De Riu G. Gustatory dysfunction: a highly specific and smell-independent symptom of COVID-19. Indian J Otolaryngol Head Neck Surg. 2020. Doi: 10.1007/s12070-020-02182-4. (First author, Corresponding author).


    32. Vaira LA, Salzano G, Deiana G, De Riu G. In response to anosmia and ageusia: common findings in COVID-19 patients. Laryngoscope. 2020;130(11):E695. (First author, Corresponding author).


    33. Vaira LA, Salzano G, Deiana G, Salzano FA, De Riu G. In response to: in reference to anosmia and ageusia: common findings in COVID-19 patients. Laryngoscope. 2020;130(9):E506. (First author, Corresponding author).


    34. Piombino P, Zace P, Vaira LA, De Riu G, Califano L. Use of absorbable membrane in diced cartilage technique for nasal dorsum restoration. J Plat Recontr Aesthet Surg. 2020;73(12):2239-2260.


    35. Hopkins C, Vaira LA, De Riu G. Self-reported olfactory loss in COVID-19: is it really a favorable prognostic factor? Int Forum Allergy Rhinol. 2020;10(7):926. 


    36. De Riu G, Vaira LA, Ligas E, Vaittinen V, Spano G, Salzano G, Piombino P. New protocol for in-house management of computer assisted orthognathic surgery. Br J Oral Maxillofac Surg. 2020;58(10):e265-e271. (Co-first author, Corresponding author).


    37. Lechien JR, Ducarme M, Place S, Chiesa-Estomba CM, Khalife M, De Riu G; Vaira LA, de Terwagne C, Machayekhi S, Marchant A; Journe F, Saussez S. Objective olfactory findings in hospitalized severe COVID-19 patients. Pathogens. 2020;9(8):627.


    38. Lechien JR. Michel J, Radulesco T, Chiesa-Estomba CM, Vaira LA, De Riu G, Sowerby L, Hopkins C, Saussez S. Clinical and radiological evaluations of COVID-19 patients with anosmia: preliminary report. Laryngoscope. 2020;130(11):2526-2531. 


    39. Petrocelli M, Ruggiero F, Baietti AM, Pandolfi P, Salzano G, Salzano FA, Lechien JR, Saussez S, De Riu G, Vaira LA. Remote psychophysical evaluation of olfactory and gustatory functions in early-stage coronavirus disease 2019 patients: the Bologna experience of 300 cases. J Laryngol Otol. 2020;134(7):571-576. (Last author, Corresponding author).


    40. Vaira LA, Hopkins C, Sandison A, Manca A, Machouchas N, Turilli D, Lechien JR, Barillari MR, Salzano G, Cossu A, Saussez S, De Riu G. Olfactory epithelium histopathological findings in long-term coronavirus disease 2019 related anosmia. J Laryngol Otol. 2020;134:1123-1127. (First author, Corresponding author).


    41. Lechien JR, Journe F, Hans S, Chiesa-Estomba CM, Mustin V, Beckers E, Vaira LA, De Riu G, Hopkins C, Saussez S. Severity of anosmia as an early symptom of COVID-19 infection may predict lasting loss of smell. Front Med. 2020;7:582802.


    42. Salzano G, Maglitto F, Vaira LA, Salzano FA, De Riu G. Ageusia, a highly specific symptom of COVID-19, for which an unaware patient may seek dental assistance. Int Dent J. 2021;71(2):85-86. 


    43. Zinellu A, Scano V, Masotto E, De Riu G, Vaira LA, Carru C, Pirina P, Babudieri S, Mangoni AA, Fois AG. The systemic inflammation index on admission is independently associated with length of stay in hospitalized COVID-19 patients. Minerva Resp Med. 2021;60:65-72.


    44. Maglitto F, Dell’Aversana Orabona G, Committeri U, Salzano G, De Fazio GR, Vaira LA, Abbate V, Bonavolontà P, Piombino P, Califano L. Virtual surgical planning and the “in-house” rapid prototyping technique in maxillofacial surgery: The current situation and future perspectives. Applied Sciences. 2021;11(3):1-13.


    45. Vaira LA, De Riu G, Ligas E, Deiana G, Vacca G, Massarelli O, Piombino P, Brevi BC. Neck dissection with harmonic instruments and electrocautery: a prospective comparative study. Oral Maxillofac Surg. 2021;25(1):75-79. (First author, Corresponding author).


    46. Lechien JR, Radulesco T, Calvo-Henriquez C, Chiesa-Estomba CM, Hans S, Barillari MR, Cammaroto G, Descamps G, Hsieh J, Vaira L, De Riu G, Sowerby L, Gengler I, Michel J, Saussez S. ACE2 & TMPRSS2 expressions in head & neck tissues: a systematic review. Head Neck Pathol. 2021;15:225-235. 


    47. Massarelli O, Vaira LA, De Riu G. Comment on: reconstruction using facial artery system-based flaps. One vascular system for multiple purposes in head and neck reconstructive surgery. Acta Otorrinolaringol Esp. 2021;72:135-136.


    48. Chiesa-Estomba CM, Lechien JR, Calvo-Henriquez C, Mayo M, Maldonado B, Maza J, Tucciarone M, Villareal I, Vaira LA, Izquierdo-Dominguez A, Alobid I. Translation and validation of the short version of the questionnaire of olfactory disorders-negative statements to Spanish. Am J Otolaryngol. 2021;42:102775.


    49. Salzano G, Dell’aversana Orabona G, Audino G, Vaira LA, Trevisiol L, D’Agostino A, Pucci R, Battisti A, Cucurullo M, Ciardiello C, Barca I, Cristofaro MG, De Riu G, Biglioli F, Valentini V, Nocini PF, Califano L. Have there been any changes in the epidemiology and etiology of maxillofacial trauma during the COVID-19 pandemic? An Italian multicenter study. J Craniofac Surg. 2021;32:1445-1447. (Corresponding author).


    50. Vaira LA, Hopkins C, Petrocelli M, Lechien JR, Cutrupi S, Salzano G, Chiesa-Estomba CM, Saussez S, De Riu G. Efficacy of corticosteroid therapy in the treatment of long-lasting olfactory disorders in COVID-19 patients. Rhinology. 2021;59:21-25. (First author, Corresponding author).


    51. Hopkins C, Surda P, Vaira LA, Lechien JR, Safarian M, Saussez S, Kumar N. Six month follow-up of self-reported loss of smell during the COVID-19 pandemic. Rhinology. 2021;59:26-31.


    52. Vaira LA, Lechien JR, Khalife M, Petrocelli M, Hans S, Distinguin L, Salzano G, Cucurullo M, Doneddu P, Salzano FA, Biglioli F, Journe F, Piana AF, De Riu G, Saussez S. Psychophysical evaluation of the olfactory function: European multicenter study on 774 COVID-19 patients. Pathogens. 2021;10:62. (First author, Corresponding author).


    53. Lechien JR, Chiesa-Estomba CM, Vaira LA, De Riu G, Cammaroto G, Chekkoury-Idrissi Y, Circiu M, Distinguin L, Journe F, de Terwangne C, Machayekhi S, Barillari MR, Calvo-Henriquez C, Hans S, Saussez S. Epidemiological, otolaryngological, olfactory and gustatory outcomes according to the severity of COVID-19: a study of 2579 patients. Eur Arch Otorhinolaryngol. 2021;278:2851-2859.


    54. Salzano FA, Vaira LA, Maglitto F, Mesolella M, De Riu G. In reference to distinct histopathology characteristics in empty nose syndrome. Laryngoscope. 2021;131(4):E1038.


    55. Lechien JR, Chiesa-Estomba CM, Radulesco T, Michel J, Vaira LA, Le Bon SD, Horoi M, Falanga C, Barillari MR, Hans S, Tucciarone M, Saussez S. Clinical features of patients who had two COVID-19 episodes: a European multicentre case series. J Intern Med. 2021;290:421-429.


    56. Lechien JR, Chiesa-Estomba CM, Vaira LA, De Riu G, Cammaroto G, Chekkoury-Idrissi Y, Circiu M, Distinguin L, Journe F, de Terwangne C, Machayekhi S, Barillari MR, Calvo-Henriquez C, Hans S, Saussez S. Correction to: epidemiological, otolaryngological, olfactory and gustatory outcomes according to the severity of COVID-19: a study of 2579 patients. Eur Arch Otorhinolaryngol. 2021;278:2861.


    57. Piombino P, Committeri U, Norino G, Vaira LA, Troise S, Maglitto F, Mariniello D, De Riu G, Califano L. Facing covid-19 pandemic: development of custom-made face mask with rapid prototyping system. J Infect Dev Ctries. 2021;15:51-7. (Corresponding author).


    58. Boscolo-Rizzo P, Menegaldo A, Fabbris C, Spinato G, Borsetto D, Vaira LA, Calvanese L, Pettorelli A, Sonego M, Frezza D, Bertolin A, Cestaro W, Rigoli R, D’Alessandro A, Tirelli G, Da Mosto MC, Menini A, Polesel J, Hopkins C. Six-month psychophysical evaluation of olfactory dysfunction in patients with COVID-19. Chem Senses. 2021;46:bjab006. 


    59. COVIDSurg Collaborative, GlobalSurg Collaborative. Timing of surgery following SARS-COV-2 infection: an international prospective cohort study. Anesthesia. 2021;76(6):748-758.


    60. Lechien JR, Chiesa-Estomba CM, Hans S, Calvo-Henriquez C, Mayo-Yanez M, Tucciarone M, Vaira LA, Saussez S, Saibene AM. Validity and reliability of the COVID-19 symptom index, an instrument evaluating severity of general and otolaryngological symptoms. Acta Otolaryngol. 2021;141:615-620.


    61. COVIDSurg Collaborative, GlobalSurg Collaborative. SARS-COV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021;108:1056-1063.


    62. Lechien JR, Hoch CC, Vaira LA, Saussez S. The interest of fluticasone nasal spray in COVID-19 related anosmia is still not demonstrated. Am J Otolaryngol. 2021;42(4):103008.


    63. Vaira LA, Lechien JR, De Riu G, Saussez S. Chemosensory dysfunction in COVID-19: is there really a correlation with viral load? Am J Otolaryngol. 2021;42:103037. (First author, Corresponding author).


    64. Petrocelli M, Cutrupi S, Salzano G, Maglitto F, Salzano FA, Lechien JR, Saussez S, Boscolo-Rizzo P, De Riu G, Vaira LA. Six-month smell and taste recovery rates in coronavirus disease 2019 patients: a prospective psychophysical study. J Laryngol Otol. 2021;135:436-441. (Last author; Corresponding author).


    65. Dell’Aversana Orabona G, Salzano G, Abbate V, Bonavolontà P, Committeri U, Seidita F, Petrocelli M, Somma T, Improta G, Vaira LA, Iaconetta G, Califano L. Malignant tumours of the parotid gland: management of the neck (including the clinically negative neck) and a literature review. Br J Oral Maxillofac Surg. 2021;59:665-671.


    66. Le Bon SD, Payen L, Prunier L, Steffens Y, Horoi M, Vaira LA, Hopkins C, Lechien JR, Saussez S. Making scents of loss of taste in COVID-19: is self-reported loss of taste due to olfactory dysfunction? A prospective study using psychophysical testing. Int Forum Allergy Rhinol. 2021;11:1504-1507.


    67. Salzano G, Maglitto F, Bisogno A, Vaira LA, De Riu G, Cavaliere M, di Stadio A, Mesolella M, Motta G, Ionna F, Califano L, Salzano FA. Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients. Acta Otorhinolaryngol Ital. 2021;41:120-130.


    68. Saussez S, Sharma S, Thiriad A, Olislagers V, Vu Duc I, Le Bon SD, Khalife M, Hans S, De Riu G, Hopkins C, Lechien JR, Vaira LA, Marchant A. Predictive factors of smell recovery in a clinical series of 288 coronavirus disease 2019 patients with olfactory dysfunction. Eur J Neurol. 2021;28:3702-3711. (Co-senior author).


    69. Vaira LA, De Vito A, Deiana G, Pes C, Giovanditto F, Fiore V, Lechien JR, Saussez S, Policicchio D, Boccaletti R, Madeddu G, Babudieri S, Pazzola A, Bandiera F, Fois AG, Piana AF, Hopkins C, De Riu G. Systemic inflammatory markers and psychophysical olfactory scores in coronavirus disease 2019 patients: is there any correlation? J Laryngol Otol. 2021;135:723-728. (First author, Corresponding author).


    70. Saussez S, Vaira LA, Chiesa-Estomba CM, Bon SL, Horoi M, Deiana G, Petrocelli M, Boelpaep P, Salzano G, Khalife M, Hans S, De Riu G, Hopkins C, Lechien JR. Short-term efficacy and safety of oral and nasal corticosteroids in COVID-19 patients with olfactory dysfunction: a European multicenter study. Pathogens. 2021;10:698. (Co-first author).


    71. Vaira LA, Deiana G, Lechien JR, De Vito A, Cossu A, Dettori M, Del Rio A, Saussez S, Madeddu G, Babudieri S, Fois AG, Cocuzza C, Hopkins C, De Riu G, Piana AF. Correlations between olfactory psychophysical scores and SARS-CoV-2 viral load in COVID-19 patients. Laryngoscope. 2021;131:2312-8. (First author, Corresponding author).


    72. Lechien JR, Saussez S, Maniaci A, Vaira LA. The study of recovery rates of COVID-19 olfactory and gustatory dysfunctions requires psychophysical evaluations. Am J Otolaryngol. 2021;42(6):103168. (Last author).


    73. Vaira LA, Calvo-Henriquez C, Mayo-Yanes M, Hoch CC, Lechien JR. Olfactory and gustatory dysfunctions are difficult to evaluate in hospitalized COVID-19 patients. Am J Otolaryngol. 2021;42(6):103169. (First author, Corresponding author).


    74. COVIDSurg Collaborative, GlobalSurg Collaborative. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021;76:1454-1464.


    75. Vaira LA, Lechien JR, Dore S, Boccaletti R, Saussez S, De Riu G. Specific therapy of olfactory disorders in COVID-19 patients is essential for the prevention of long-term dysfunction. Indian J Otolaryngol Head Neck Surg. 2021. Doi: 10.1007/s12070-021-02818-z. (First author, Corresponding author).


    76. Lechien JR, Diallo AO, Dachy B, Le Bon SD, Maniaci A, Vaira LA, Saussez S. COVID-19: post-vaccine smell and taste disorders: report of 6 cases. Ear Nose Throat J. 2021. Doi: 10.1177/01455613211033125.


    77. Boscolo-Rizzo P, Hummel T, Hopkins C, Dibattista M, Menini A, Spinato G, Fabbris C, Emanuelli E, D’Alessandro A, Marzolino R, Zanelli E, Cancellieri E, Cargnelutti K, Fadda S, Borsetto D, Vaira LA, Gardenal N, Polesel J, Tirelli G. High prevalence of long-term olfactory, gustatory and chemesthesis dysfunction in post-COVID-19 patients: a matched case-control study with one-year follow-up using a comprehensive psychophysical evaluation. Rhinology. 2021;59:517-527.


    78. Lechien JR, Hopkins C, Vaira LA, Saussez S. SARS-CoV-2 vaccination may help patients with persistent COVID-19 smell dysfunction. Ear Nose Throat J. 2021. Doi: 10.1177/01455613211044770.


    79. Lechien JR, Saussez S, Vaira LA, Hans S. Post-COVID-19 dysphonia may have several origins. Indian J Otolaryngol Head Neck Surg. 2021. Doi:10.1007/s12070-021-02951-9.


    80. Bussu F, Rizzo D, Saderi L, Piras A, De Luca LM, De Riu G, Vaira LA, Serra A, Altrudo P, Delogu D, Dettori I, Riu FG, Angioj F, Firino L, Govoni R, Ibba G, Lai V, Mura E, Paglietti B, Piu C, Puggioni A, Rimini E, Rocca G, Serra C, Uzzau S, Rubino S, Sotgiu G. “Swab Team” in the SARS-CoV-2 outbreak containment among healthcare workers. J Infect Dev Ctries. 2021;30:1640-1645.


    81. Salzano G, Perri F, Maglitto F, Togo G, De Fazio GR, Apolito M, Calabria F, Laface C, Vaira LA, Committeri U, Balia M, Pavone E, Aversa C, Salzano FA, Abbate V, Ottaiano A, Cascella M, Santorsola M, Fusco R, Califano L, Ionna F. Pre-treatment neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictors of occult cervical metastasis in clinically negative neck supraglottic and glottic cancer. J Pers Med. 2021;11;1252.


    82. Lechien JR, Chiesa-Estomba CM, Vaira LA, Saussez S, Hans S. COVID-19 reinfection and second episodes of olfactory and gustatory dysfunctions: report of first cases. Ear Nose Throat J. 2022;101:499-500. 


    83. Boscolo-Rizzo P, Giuda F, Polesel J, Marcuzzo AV, Antonucci P, Capriotti V, Sacchet E, Cragnolini F, D’Alessandro A, Zanelli E, Marzolino R, Lazzarini C, Tofanelli M, Gardenal N, Borsetto D, Hopkins C, Vaira LA, Tirelli G. Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study. Eur Arch Otorhinolaryngol. 2022;279:515-520.


    84. Vaira LA, De Vito A, Deiana G, Pes C, Giovanditto F, Fiore V, Lechien JR, Le Bon SD, Saussez S, Madeddu G, Babudieri S, Pazzola A, Bandiera F, Fois AG, Piana AF, Hopkins C, De Riu G. Correlations between IL-6 serum level and olfactory dysfunction severity in COVID-19 patients: a preliminary study. Eur Arch Otorhinolaryngol. 2022;12:103-107. (First author, Corresponding author).


    85. Salzano G, Dell’aversana Orabona G, Abbate V, Vaira LA, Committeri U, Bonavolontà P, Piombino P, Maglitto F, Russo C, Varricchio S, Attanasi F, Turri-Zanoni M, De Riu G, Califano L. The prognostic role of the pre-treatment neutrophil to lymphocyte ratio (NLR) and tumor depth of invasion (DOI) in early-stage squamous cell carcinomas of the oral tongue. Oral Maxillofac Surg. 2022;26:21-32.


    86. Piombino P, Troise S, Maglitto F, Barone S, Sani L, Committeri U, Norino G, Bonavolontà P, Salzano G, Vaira LA, De Riu G, Califano L. Management of orbital floor fractures: our experience in 10 years. Indian J Otolaryngol Head Neck Surg. 2022;74:547-554.


    87. Amadu AM, Vaira LA, Lechien JR, Scaglione M, Saba L, Lampus ML, Profili SG, Le Bon SD, Salzano G, Maglitto F, Saussez S, Boscolo-Rizzo P, Hopkins C, De Riu G. Analysis of the correlations between the severity of lung involvement and olfactory psychophysical scores in coronavirus disease 2019 (COVID-19) patients. Int Forum Allergy Rhinol. 2022;12:103-107. (Co-first author, Corresponding author).


    88. Vaira LA, Podda L, Doneddu P, Careddu MG, Fozza C, De Riu G. Secondary thrombocytopenia after SARS-CoV-2 vaccine: report of a case of hemorrhage and hematoma after minor oral surgery. J Stomatol Oral Maxillofac Surg. 2022;123:95-97. (First author, Corresponding author).


    89. COVIDSurg Collaborative, GlobalSurg Collaborative. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2022;77:28-39.


    90. Massarelli O, Vaira LA, De Riu G. A new aesthetic pretrichial approach for upper third-facial fractures and pathologies: the “Crown incision”. J Plast Reconstr Aesthet Surg. 2022;75:788-796.


    91. Vaira LA, De Vito A, Lechien JR, Chiesa-Estomba CM, Mayo-Yamez M, Calvo-Henriquez C, Saussez S, Madeddu G, Babudieri S, Boscolo-Rizzo P, Hopkins C, De Riu G. New onset of smell and taste loss are common findings also in patients with symptomatic COVID-19 after complete vaccination. Laryngoscope. 2022;132:419-421. (First author, Corresponding author).


    92. Vaira LA, Salzano G, Le Bon S, Maglio A, Petrocelli M, Steffens Y, Ligas E, Maglitto F, Lechien JR, Saussez S, Vatrella A, Salzano FA, Boscolo-Rizzo P, Hopkins C, De Riu G. Prevalence of persistent olfactory disorders in patients with COVID-19: a psychophysical case-control study with 1-year follow-up. Otolaryngol Head Neck Surg. 2022;167:183-186. (First author, Corresponding author).


    93. Vaira LA, Lechien JR, Salzano G, Maglitto F, Saussez S, De Riu G. The role of nasal immunoglobulins in the recovery of olfactory function in COVID-19 patients. Am J Otolaryngol. 2022;43:103301. (First author, Corresponding author).


    94. Vaira LA, De Vito A, Lechien JR, Chiesa-Estomba CM, Mayo-Yamez M, Calvo-Henriquez C, Boscolo-Rizzo P, Hopkins C, De Riu G. In response to smell and taste loss in COVID-19 after complete vaccination: correspondence. Larygnoscope. 2022;132:E19 (First author, Corresponding author).


    95. Chiesa-Estomba CM, Grana M, Medela A, Sistiga-Suarez JA, Lechien JR, Calvo-Henriquez C, Mayo-Yanez M, Vaira LA, Grammatica A, Cammaroto G, Ayad T, Fagan JJ. Machine learning alghorithms as a computer-assisted decision tool for oral cancer prognosis and management decisions: a systematic review. ORL J Otorhinolaryngol Relat Spec. 2022;84:278-288.


    96. Salzano G, Togo G, Maglitto F, Borriello G, Perri F, Audino G, Vaira LA, Maglione MG, Petrocelli M, Califano L, Ionna F. Trans-oral robotic surgery: 14 cases of pleomorphic adenoma of the parapharyngeal space. J Craniofac Surg. 2022;33:1587-1590.


    97. Vaira LA, Lechien JR, Saussez S, Hopkins C, De Riu G. In reply to: IL-6 serum level and olfactory dysfunction severity in COVID-19: correspondence. Eur Arch Otorhinolaryngol. 2022;279:2209-2210. (First author, Corresponding author).


    98. Lechien JR, Calvo-Henriquez C, Mayo-Yanez M, El Ayoubi M, Vaira LA, Maniaci A. The study of laryngopharyngeal reflux needs adequate animal model. Eur Arch Otorhinolaryngol. 2022;279:3227-3228. 


    99. Vaira LA, Gessa C, Deiana G, Salzano G, Maglitto F, Lechien JR, Saussez S, Piombino P, Biglio A, Biglioli F, Boscolo-Rizzo P, Hopkins C, Parma V, De Riu G. The effects of persistent olfactory and gustatory dysfunctions on quality of life in long-COVID-19 patients. Life. 2022;12:141. (First author, Corresponding author).


    100. Mayo-Yanez M, Chiesa-Estomba CM, Lechien JR, Calvo-Henriquez C, Vaira LA, Cabo-Varela I. Long-term outcomes and cost-effectiveness of a magnet-based valve voice prosthesis for endoprosthesis leakage treatment. Eur Arch Otorhinolaryngol. 2022;279:4167-4172.


    101. Maglitto F, Salzano G, Longo F, Di Bernardo E, D’alessio V, Fusco R, Aversa C, Pavone E, Pontone M, Marciano ML, Togo G, De Fazio GR, Ordano D, Maglione MG, Vaira LA, Borgonzani M, Salzano FA, Maiolino P, Caligano L, Ionna F, Perri F. Electrochemotherapy as palliative treatment in patients with recurrent and/or metastatic head and neck tumours: features analysis for an early determination of the partial responsive patients. Eur Rev Med Pharmacol Sci. 2022;26:1350-1363.


    102. Boscolo-Rizzo P, Tirelli G, Meloni P, Hopkins C, Madeddu G, De Vito A, Gardenal N, Valentinotti R, Tofanelli M, Borsetto D, Lechien JR, Polesel J, De Riu G, Vaira LA. COVID-19-related smell and taste impairment with widespread diffusion of SARS-CoV-2 omicron variant. Int Forum Allergy Rhinol. 2022;12:1273-1281. (Last author)


    103. Vaira LA, De Riu G, Salzano G, Maglitto F, Boscolo-Rizzo P, Lechien JR. In response to clinical features of parosmia associated with COVID-19 infection. Laryngoscope, 2022;132:E28-E29. (First author).


    104. Giovanditto F, Soma D, Vaira LA, Pispero A, Lombardi N, Ristoldo F, Mariani U, Pizzi S, Isola A, Smania P, Albanese M, D’agostino A, Appendino P, Scatà E, Raho MT, Gobbi R, Massarelli O, Lumbau A, Spano G, De Riu G. Recommendations for a safe restart of elective aerosol-generating oral surgery procedures following the COVID-19 pandemic outbreak: an Italian multicenter study. J Cranio Maxillofac Surg. 2022;50:462-467.


    105. Di Stadio A, D’Ascanio L, Vaira LA, Cantone E, De Luca P, Cingolani C, Motta G, De Riu G, Vitelli F, Spriano G, De Vincentiis M, Camaioni A, La Mantia I, Ferreli F, Brenner MJ. Ultramicronized palmitoylethanolamide and luteolin supplement combined with olfactory training to treat post-COVID-19 olfactory impairment: a multi-center double-blinded randomized placebo-controlled clinical trial. Curr Neuropharmacol. 2022;20:2001-2012.


    106. Lechien JR, Saussez S, Maniaci A, Boscolo-Rizzo P, Vaira LA. The detection of smell disorder depends on the clinical tools. Am J Otolaryngol. 2022;43:103445. (Last author)


    107. Boscolo-Rizzo P, Hopkins C, Menini A, Dibattista M, Cancellieri E, Gardenal N, Tofanelli M, Valentinotti R, Lechien JR, Vaira LA, Tirelli G. Parosmia assessment with structured questions and its functional impact in patients with long-term COVID-19-related olfactory dysfunction. Int Forum Allergy Rhinol. 2022. Doi: 10.1002/alr.23054.


    108. Vaira LA, De Riu G, Salzano G, Maglitto F, Boscolo-Rizzo P, Lechien JR. The rate of persistent COVID-19 related chemosensory dysfunctions can be established only after one year. Oral Dis. 2022. Doi: 10.1111/odi.14298. (First author, Corresponding author).


    109. Salzano G, Audino G, Friscia M, Vaira LA, Biglio A, Maglitto F, Committeri U, Piombino P, Bonavolontà P, Petrocelli M, Perrotta S, Califano L. Bad splits in bilateral sagittal split osteotomy: A retrospective comparative analysis of the use of different tools. J Craniomaxillofac Surg. 2022;50:543-549. 


    110. Vaira LA, De Riu G, Boscolo-Rizzo P, Hopkins C, Lechien JR. In response to: olfactory dysfunction in COVID-19, new insights from a cohort of 353 patients: the ANOSVID study. J Med Virol. 2022;94:5086-5087. (First author, Corresponding author).


    111. Lechien JR, Hamdan AL, Saibene A, Vaira LA. In response to assessment of laryngopharyngeal reflux and obstructive sleep apnea: a population-based study. Laryngoscope. 2022. Doi: 10.1002/lary.30301. (Last Author)


    112. Vaira LA, Boscolo-Rizzo P, Bui Quoc E, Bandekela P, Saussez S, Lechien JR. The study of olfactory dysfunction in SARS-CoV-2 variants. Eur Arch Otorhinolaryngol. 2022. Doi: 10.1007/s00405-022-07548-8. (First author).


    113. Lechien JR, Hans S, Vaira LA, Boscolo-Rizzo P, De Marrez LG, Baudouin R, Gheorghe A, Sebestyen A, Loubieres C, Karkos PD, Saussez S. A prospective controlled study investigating odor identification in laryngopharyngeal reflux. Otolaryngol Head Neck Surg. 2022. Doi: 10.1177/01945998221117469. 


    114. Boscolo-Rizzo P, Polesel J, Vaira LA. Smell and taste dysfunction after covid-19. BMJ. Doi: 10.1136/bmj.01653. (Last Author).


    115. Lechien JR, Vaira LA, Saussez S. Prevalence and 24-month recovery of olfactory dysfunction in COVID-19 patients: a multicenter prospective study. J Intern Med. 2022;378:o1653.


    116. Boscolo-Rizzo P, Hopkins C, Vaira LA. Otolaryngologic manifestations of the ongoing outbreak of human monkeypox: ENT specialists should be on the alert. Eur Arch Otorhinolaryngol. 2022. Doi: 10.1007/s00405-022-07601-6. (Last Author).


    117. Arena A, Committeri U, Maglitto F, Salzano G, Dell’Aversana Orabona G, Vaira LA, Piombino P, Apolito M, De Fazio G, Califano L. Three different types of fat grafting for facial systemic sclerosis: a case series. J Clin Med. 2022;11:5489.


    118. Piombino P, Abbate V, Sani L, Troise S, Committeri U, Carraturo E, Maglitto F, De Riu G, Vaira LA, Califano L. Virtual surgical planning in orthognathic surgery: two software platforms compared. Appl Sci. 2022;12:9364.


    119. Lechien JR, Vaira LA, Saussez S. Effectiveness of olfactory training in COVID-19 patients with olfactory dysfunction: a prospective study. Eur Arch Otorhinolaryngol. 2022. Doi: 10.1007/s00405-022-07665-4.


    120. Saibene AM, Allevi F, Calvo-Henriquez C, Dauby N, Dondossola D, Hervochon R, Lechien JR, Lobo-Duro D, Locatello LG, Maniaci A, Mannelli G, Mayo-Yanez M, Maza-Solano J, Radulesco T, Tan N, Tincati C, Tucciarone M, Vaira LA, Sowerby L. Comprehensive management of paranasal sinus fungus balls: a young-IFOS consensus statement. Int Forum Allergy Rhinol. 2022. Doi: 10.1002/alr.23093.


    121. Lechien JR, Vaira LA, Le Bon SD, Geerts R, Boscolo-Rizzo P, Saussez S. Validity and reliability of a French version of the olfactory disorder questionnaire. J Otolaryngol Head Neck Surg. 2022;51:36.


    122. Mayo-Yanez MM, Vaira LA, Lechien JR, Chiesa-Estomba CM, Calvo-Henriquez C, Cabo-Varela I. Commentary on periprosthetic leakage in tracheoesophageal prosthesis: proposal of a standardized therapeutic algorithm. Otolaryngol Head Neck Surg. 2022. Doi: 10.1177/01945998211073058.


    123. Piombino P, Sani L, Sangu G, Carraturo E, De Riu G, Vaira LA, Maglitto F, Califano L. Titanium internal fixator in maxillofacial surgery: is it necessary? A systematic review and meta-analysis. J Craniofac Surg. 2022. Doi: 10.1097/SCS.0000000000009006.


    124. Vaira LA, De Riu G, Salzano G, Maglitto F, Boscolo-Rizzo P, Lechien JR. COVID-19 related persistent olfactory disorders represent an unprecedented challenge. Am J Otolaryngol. 2022. Doi: 10.1016/j.amjoto.2022.103667. (First author, corresponding author).


    125. Vaira LA, Lechien JR, Deiana G, Salzano G, Maglitto F, Piombino P, Mazzatenta A, Boscolo-Rizzo P, Hopkins C, De Riu G. Prevalence of olfactory dysfunction in D614G, alpha, delta and omicron waves: a psychophysical case-control study. Rhinology. 2022. Doi: 10.4193/Rhin22.294. (First author, corresponding author).


    126. Lechien JR, Saussez S, Mayo-Yanez M, Iannella G, Vaira LA. Reflux symptoms may develop in cases of throat mucosa injury, stress and related-autonomic nerve dysfunction. Am J Otolaryngol. 2022;44:103687. Doi: 10.1016/j.amjoto.2022.103687. (Last author)


    127. Lechien JR, Cheikj-Youssef R, Maniaci A, Mayo-Yanez M, Iannella G, Vaira LA. Transcutaneous electrical acupoint stimulation, autonomic nerve dysfunction and laryngopharyngeal reflux. Eur Arch Otorhinolaryngol. 2022. Doi: 10.1007/s00405-022-07740-w. (Last author)


    128. Vaira LA, Deiana G, Maglitto F, Salzano G. Post-viral olfactory loss: what we learned from the SARS-CoV-2 pandemic. Life. 2022;12:1868. (First author, corresponding author).


    129. Salzano G, Togo G, Maffia F, Vaira LA, Maglitto F, Committeri U, Fusco R, Maglione MG, Nocini R, De Luca P, Guida A, Di Stadio A, Ferrara G, Califano L, Ionna F. Early-stage oral tongue squamous cell carcinoma and a positive sentinel lymph node biopsy: description of a prognostic correlation between pre-treatment inflammatory biomarkers, the depth of invasion and the worst pattern of invasion. J Pers Med. 2022. Doi: 10.3390/jpm12111931. (Corresponding author)


    130. Vaira LA, De Riu G, Boscolo-Rizzo P, Hopkins C, Lechien JR. In reference to intranasal corticosteroid treatment on recovery of long-term olfactory dysfunction due to COVID-19. Laryngoscope. Doi: 10.1002/lary.30505. (First author, corresponding author).


    131. Vaira LA, Rizzo D, Murrocu C, Zullo CF, Dessy M, Mureddu L, Ligas E, Salzano G, Biglio A, Mayo Yanez M, Lechien JR, Piombino P, Bussu F, De Riu G. Electrocautery, Harmonic, and Thunderbeat instruments in parotid surgery: a retrospective comparative study. J Clin Med. 2022;11:7414. (First author, corresponding author).


    132. Vaira LA, Lechien JR, De Riu G, Saussez S. The trajectories of olfactory dysfunction from the first to the omicron wave: are we getting over it? Pathogens. 2022;12:10. (First author, corresponding author).


    133. Saussez S, Vaira LA, De Riu G, Lechien JR. Therapies for COVID-19-related persistent olfactory disorders: one of the good fruits of the pandemic. Pathogens. 2023;12:72. (Corresponding author).


    134. Di Stadio A, Bernitsas E, La Mantia I, Brenner MJ, Ralli M, Vaira LA, Colizza A, Cavaliere C, Laudani M, Frohman T, De Vincentis M, Frohman EM, Altieri M. Targeting neuroinflammation to alleviate chronic olfactory dysfunction in long COVID: a role for investigating disease-modifying therapy (DMT)? Life. 2023;13:226.


    135. Mayo-Yanez M, Diaz-Diaz A, Calvo-Henriquez C, Lechien JR, Vaira LA, Figueroa A. Diamine oxidase activity deficit and idiopathic rhinitis: a new subgroup of non-allergic rhinitis? Life. 2023;13:240.


    136. Vaira LA, Sergnese S, Salzano G, Maglitto F, Arena A, Carraturo E, Abbate V, Committeri U, Vellone V, Biglio A, Lechien JR, De Riu G. Are YouTube videos a useful and reliable source of information for patients with temporomandibular joint disorders? J Clin Med. 2023; 12:817. (First author, corresponding author).


    137. Abbate V, Committeri U, Troise S, Bonavolontà P, Vaira LA, Gabriele G, Biglioli F, Tarabbia F, Califano L, Dell’aversana Orabona G. Virtual surgical reduction in atrophic edentulous mandible fractures: a novel approach based on “in house2 digital work-flow featured application: virtual surgical planning in cranio-facial traumatology. Appl Sci. 2023;13;1474


    138. Vaira LA, Massaiu A, Massaiu G, Salzano G, Maglitto F, Lechien JR, Biglio A, Visaloco G, Piombino P, Biglioli F, De Riu G. Efficacy of auriculotherapy in the control of pain, edema, and trismus following surgical extraction of the lower third molars: a split-mouth, randomized, placebo-controlled, and triple-blind study. Oral Maxillofac Surg. 2023 Doi: 10.1007/s10006-023-01140-y. (First author, corresponding author).


    139. Piombino P, Esposito E, Committeri U, Barone S, Arena A, Cataldo R, Carraturo E, Vaira LA, De Riu G, Mariniello D, Califano L. Facial soft tissue thickness measurement method and relationship with BMI, age and sex. J Stomatol Oral Maxillofac Surg. 2023. Doi: 10.1016/j.jormas.2023.101420.


    140. Mayo-Yanez M, Vaira LA, Maniaci A, Cabo-Varela I. Enlarged tracheoesophageal fistula following total laryngectomy: a common problem and a therapeutic challenge. Dysphagia. 2023. Doi: 10.1007/s00455-023-10562-5.


    141. Vaira LA, De Riu G, Mayo-Yanez M, Gengler IM, Lechien JR. Prevalence of chemosensitive disorders with Omicron infections and the possible impacts of vaccination. Int J Infect Dis. 2023. Doi: 10.1016/j.ijid.2023.02.007. (First author, corresponding author).


    142. Vaira LA, Lechien JR, Salzano G, Maglitto F, Boscolo-Rizzo P, Hopkins C, De Riu G. SARS-CoV-2 effects on psychophysical olfactory scores: prospective study with evaluation before and 60-days after infection. Otolaryngol Head Neck Surg. 2023 Doi: 10.1002/ohn.166. (First author, corresponding author).


    143. Salzano G, Maglitto F, Calvanese C, Apolito M, Buono S, Franco P, Perri F, Vaira LA, De Luca R, Salzano FA, Caligano L, Ionna F. Pharyngocutaneous fistula in salvage laryngectomy: use of the stapler versus manual suturing technique. Indian J Otolaryngol Head Neck Surg. 2023 Doi: 10.1007/s12070-023-03587-7.


    144. Boscolo-Rizzo P, Hummel T, Invitto S, Spinato G, Tomasoni M, Emanuelli E, Tofanelli M, Cavicchia A, Grill V, Vaira LA, Lechien JR, Borsetto D, Polesel J, Dibattista M, Menini A, Hopkins C, Tirelli G. Psychophysical assessment of olfactory and gustatory function in post-mild COVID-19 patients: a matched case-control study with two-year follow-up. Int Forum Allergy Rhinol. 2023 Doi: 10.1002/alr.23148.


    145. Petrocelli M, Togo G, Ricci S, Zaneli F, Cutrupi S, Baietti A, Bonavolontà P, Califano L, Vaira LA, Scarpa A, Di Stadio A, Salzano G. Dermal substitutes and skin grafts in the reconstruction of post-traumatic total scalp avulsion: a case series. J Clin Med. 2023;12:2167


    146. Lechien JR, Wajsblat S, Horoi M, Boscolo-Rizzo P, Le Bon SD, Vaira LA, Saussez S. Comparison of prevalence and evolution of COVID-19 olfactory disorders in patients infected by D614 (wild) and B.1.1.7. Alpha variant: a brief report. Eur Arch Otorhinolaryngol. 2023. Doi: 10.1007/s00405-023-07923-z.


    147. Committeri U, Barone S, Salzano G, Arena A, Borriello G, Giovacchini F, Fusco R, Vaira LA, Scarpa A, Abbate V, Ugga L, Piombino P, Ionna G, Califano L. Support tools in the differential diagnosis of salivary gland tumors through inflammatory biomarkers and radiomics metrics: a preliminary study. Cancer. 2023;15:1876.


    148. Boscolo-Rizzo P, Hummel T, Invitto S, Spinato S, Vaira LA, Lechien JR, Menini A, Hopkins C, Tirelli G. Reply to: it is necessary to assess olfactory and gustatory functions in post-COVID-19 patients due to the omicron variant infection. Int Forum Allergy Rhinol. 2023. Doi. 10.1002/alr.23159.


    149. Vaira LA, Saussez S, Maniaci A, Boscolo-Rizzo P, Hans S, Lechien JR. Post-thyroidectomy dysphonia and swallowing symptoms: the role of cricopharyngeal sphincter. Am J Otolaryngol. 2023. Doi: 10.1016/j.amjoto.2023.103910. (First author).


    150. Lechien JR, Chiesa-Estomba CM, Maniaci A, Vaira LA, Gengler I. Dysphagia after supraglottic laryngeal cancer surgery. Am J Otolaryngol. 2023. Doi: 10.1016/j.amjoto.2023.103925


    151. Committeri U, Arena A, Carraturo E, Barone S, Salzano G, Mariniello D, De Riu G, Vaira LA, Giovacchini F, Califano L, Piombino P. Minimally invasive harvesting technique for costal cartilage graft: donor site, morbidity and aesthetic outcomes. J Clin Med. 2023;12:3424.


    152. Vaira LA, Boscolo-Rizzo P, Lechien JR, Mayo-Yanez M, Petrocelli M, Pistidda L, Salzano G, Maglitto F, Hopkins C, De Riu G. Olfactory recovery following Omicron variant infection: a psychphysical prospective case-control study with 6 month follow-up. J Laryngol Otol. 2023. Doi: 10.1017/S0022215123000877. (First author, corresponding author).


    153. De Riu G, Soma D, Biglio A, Raho MT, Mura D, Michelon F, Salzano G, Piombino P, Lechien JR, Vaira LA. Primary reconstruction of total maxillectomy with custom-made subperiosteal implant and temporal muscle flap: a case report. Appl Sci. 2023;13:6269. (Last author, corresponding author).


    154. Massarelli O, Vaira LA, Crimi S, Salzano G, Latini L, Bianchi A, Gennaro P, De Riu G. Tongue Reconstruction with Buccinator Myomucosal Island Flaps: Technical Considerations, Oncologic Safety, Functional Outcomes and QoL Assessment—A Retrospective Observational Study. J Pers Med. 2023;13:879. (Co-first author, corresponding author).


    155. Salzano G, Maffìa F, Vaira LA, Committeri U, Copelli C, Maglitto F, Manfuso A, Abbate V, Bonavolontà P, Scarpa A, Califano L, Dell’Aversana Orabona G. Locoregional flaps for the recontruction of midface skin defects: a collection of key surgical techniques. J Clin Med. 2023;12:3700.


    156. Lechien JR, Maniaci A, Gengler IM, Mayo-Yanez M, Vaira LA. Asthma, chronic rhinosinusitis and laryngopharyngeal reflux. Am J Otolaryngol. 2023. Doi: 10.1016/j.amjoto.2023.103953. (Last author)


    157. Boscolo-Rizzo P, Tirelli G, Meloni P, Hopkins C, Lechien JR, Madeddu G, Bonini P, Gardenal N, Cancelleri E, Lazzarin C, Borsetto D, De Vito A, De Riu G, Vaira LA. Recovery from olfactory and gustatory dysfunction following COVID-19 acquired during Omicron BA.1 wave in Italy. Am J Otolaryngol. 2023. Doi: 10.1016/j.amjoto.2023.103944. (Last author)


    158. Rodriguez-Lorenzana P, Mayo-Yanez M, Chiesa-Estomba CM, Vaira LA, Lechien JR, Maniaci A, Cabo-Varela I. Cost-Effectiveness Study of Double-Flange Voice Prostheses in the Treatment of Periprosthetic Leakage in Laryngectomized Patients. J Pers Med. 2023;13:1064.


    159. Chiesa-Estomba CM, Lechien JR, Vaira LA, Bruet A, Cammaroto G, Mayo-Yanez M, Sanchez-Barrueco A, Saga-Gutierrez C. Exploring the potential of Chat-GPT as a supportive tool for sialendoscopy clinical decision making and patient information support. Eur Arch Otorhinolaryngol. 2023. Doi: 10.1007/s00405-023-08104-8


    160. Vaira LA, De Riu G. Temporomandibular joint disorders: functional and conservative treatment. J Clin Med. 2023;12:4772. (First author, corresponding author).


    161. Liu ZY, Vaira LA, Boscolo-Rizzo P, Walker A, Hopkins C. Post-viral olfactory loss and parosmia. BMJ Med. 2023. Doi: 10.1136/bmjmed-2022-000382.


    162. Lechien JR, Saussez S, Vaira LA, De Riu G, Boscolo-Rizzo P, Tirelli G, Michel J, Radulescon T. Effectiveness of platelet-rich plasma for COVID-19-related olfactory dysfunction: a controlled study. Otolaryngol Head Neck Surg. 2023. Doi: 10.1002/ohn.460.


    163. Rodriguez A, Maniaci A, Vaira LA, Saussez S, Lechien JR. Xerostomia, sticky saliva and dysphonia. Eur Arch Otorhinolaryngol. 2023. Doi: 10.1007/s00405-023-08171-x


    164. Vaira LA, Lechien JR, Abbate V, Allevi F, Audino G, Beltramini GA, Bergonzani M, Bolzoni A, Committeri U, Crimi S, Gabriele G, Lonardi F, Maglitto F, Petrocelli M, Pucci R, Saponaro G, Tel A, Vellone V, Chiesa-Estomba CM, Boscolo-Rizzo P, Salzano G, De Riu G. Accuracy of ChatGPT-Generated Information on Head and Neck and Oromaxillofacial Surgery: A Multicenter Collaborative Analysis. Otolaryngol Head Neck Surg. 2023. Doi: 10.1002/ohn.489. (First author, corresponding author).


    165. Vaira LA, Massarelli O, Lechien JR, Chiesa-Estomba CM, Ayad T, De Riu G. Tunnelized facial artery myomucosal island flap: a modification of the FAMM flap that enhance its reconstructive versatility. Indian J Otolaryngol Head Neck Surg. 2023. Doi: 10.1007/s12070-023-04169-3. (First author, corresponding author).


    166. Lechien JR, Maniaci A, Gengler I, Hans S, Chiesa-Estomba CM, Vaira LA. Validity and reliability of an instrument evaluating the performance of intelligent chatbot: the Artificial Intelligence Performance Instrument (AIPI). Eur Arch Otorhinolaryngol. 2023. doi: 10.1007/s00405-023-08219-y. (Last author)


    167. Frosolini A, Franz L, Benedetti S, Vaira LA, de Filippis C, Gennaro P, Marioni G, Gabriele G. Assessing the accuracy of ChatGPT references in head and neck and ENT disciplines. Eur Arch Otorhinolaryngol. 2023. doi: 10.1007/s00405-023-08205-4. 


    168. Gonzalez-Rodriguez H, Mayo Yanez M, Saibene AM, Allevi F, Chiesa-Estomba C, Vaira LA, Lechien JR. Indications, Efficacy, Safety, and Clinical Outcomes of 585 nm Pulsed Dye Laser in Non-Malignant Laryngeal Lesions: A Systematic Review. J Pers Med. 2023. Doi: 10.3390/jpm13091374.


    169. Boscolo-Rizzo P, Spinato G, Hopkins C, Marzolino R, Cavicchia A, Zucchini S, Borsetto D, Lechien JR, Vaira LA, Tirelli G. Evaluating long-term smell or taste dysfunction in mildly symptomatic COVID-19 patients: a 3-years follow-up study. Eur Arch Otorhinolaryngol. 2023. Doi: 10.1007/s00405-023-08227-y.


    170. Lechien JR, Gorton A, Robertson J, Vaira LA. Is ChatGPT-4 accurate in proofread a manuscript in otorhinolaryngology-head and neck surgery? Otolaryngol Head Neck Surg. 2023. Doi: 10.1002/ohn.526. (Last author)


    171. Abbate V, Barone S, Borriello G, Troise S, Bonavolontà P, Pacella D, Vaira LA, Turri-Zanoni M, Navarro Cuéllar C, Califano L, Dell’Aversana Orabona G. Diagnostic performance of inflammatory biomarkers and cytological analysis in salivary gland tumors. Head Neck. 2023. Doi: 10.1002/hed.27528.


    172. Biglio A, Rossetti G, Gibelli DM, Dolci C, Cappella A, Allevi F, Vaira LA, De Riu G, Sforza C, Biglioli D. Three-dimensional evaluation of symmetry in facial palsy reanimation using stereophotogrammetric devices: a series of 15 cases. J Craniomaxillofac Surg. 2023. Doi: 10.1016/j.jcms.2023.09.011.


    173. Mata-Pose L, Mayo-Yanez M, Chiesa-Estomba CM, Lechien JR, Vaira LA, Maniaci A, Saibene AM, Calvo-Henriquez C, Cabo-Varela I. Velopharyngeal incompetence in musicians: a state-of-the-art review. J Pers Med. 2023;13:1477


    174. Chiesa-Estomba CM, Lechien JR, Vaira LA, Brunet A, Cammaroto G, Mayo-Yanez M, Sanchez-Barrueco A, Saga-Gutierrez C. Correction: exploring the potential of Chat-GPT as a supportive tool for sialendoscopy clinical decision making and patient information support. Eur Arch Otolaryngol. 2023. Doi: 10.1007/s00405-023-08267-4


    175. Lechien JR, Vaira LA, Chiesa-Estomba CM. Laryngeal verrucous cell carcinoma. Curr Opin Otolaryngol Head Neck Surg. 2023. Doi: 10.1097/MOO. 0000000000000910 


    176. Troise S, Committeri U, Barone S, Gentile D, Arena A, Salzano G, Bonavolontà P, Abbate V, Romano A, Dell’aversana Orabona G, Vaira LA, De Riu G, Califano L, Piombino P. Epidemiological analysis of 120 patients from 2010 to 2022 with isolated blowout fractures of orbital floor: correlation between demographic characteristics and fracture area. J Craniomaxillofac Surg. 2023; Doi: 10.1016/j.jcms.2023.10.007.


    177. Lechien JR, Bobin, Vaira LA. Usefulness of pepsin saliva measurement for the detection of primary burning mouth syndrome related to reflux. Eur Arch Otorhinolaryngol. 2023. Doi: 10.1007/s00405-023-08317-x. (Last author)


    178. Di Bello F, Scandurra C, Muzii B, Colla’ Ruvolo C, Califano G, Mocini E, Creta M, Napolitano L, Morra S, Fraia A, Bochicchio V, Salzano G, Vaira LA, Mangiapia F, Motta G, Motta G, Maldonado NM, Longo N, Cantone E. Are Excessive Daytime Sleepiness and Lower Urinary Tract Symptoms the Triggering Link for Mental Imbalance? An Exploratory Post Hoc Analysis. Journal of Clinical Medicine. 2023; 12(22):6965. 


    179. Boscolo-Rizzo P, Hummel T, Spinato G, Vaira LA, Menini A, Hopkins C, Tirelli G. Olfactory and gustatory function 3 years after mild COVID-19 – A cohort psychophysical study. JAMA Otolaryngol Head Neck Surg. 2023. Doi: 10.1001/jamaoto.2023.3603


    180. Vaira LA, De Riu G, Mayo-Yanez M, Boscolo-Rizzo P, Lechien JR. The importance of identifying risk factors for the persistence of COVID-19 related olfactory disorders. Am J Otolaryngol. 2023. Doi: 10.1016/j.amjoto.2023.104114. (first author, corresponding author)


    181. Di Bello, F, Pezone, G, Muzi, B, Cilio S, Collà Ruvolo C, Scandurra C, Mocini E, Creta M, Morra S, Bochicchio V, Salzano G, Vaira LA, Mangiapia F, Motta G, Maldonato NM, Longo N, Cantone E, Califano G. Lower urinary tract symptoms in young-middle aged males with a diagnosis of obstructive sleep apnea syndrome. Neurourol Urodyn. 2023; 1-9. doi:10.1002/nau.25338


    182. Abbate V, Troise S, Togo G, Barone S, Bonavolontà P, Pacella D, Vaira LA, Committeri U, Tel A, Robiony M, Califano L, Dell’aversana Orabona G. Impact of sarcopenia on survival of patients with malignant salivary glands tumors. Otolaryngol Head Neck Surg. 2023. Doi: 10.1002/ohn.608


    183. Petrocelli M, Ruggiero F, Allegri D, Cutrupi S, Baietti AM, Salzano G, Maglitto F, Manfuso A, Copelli C, Barca I, Cristofaro MG, Galvano F, Loche VP, Gemini P, Tewfik K, Burlini D, Bernardi M, Bianchi FA, Catanzaro S, Ascani G, Consorti G, Balercia P, Braconi A, Scozzaro C, Catalfamo L, De Rinaldis D, De Ponte FS, Tarabbia F, Biglioli F, Giovacchini F, Tullio A, Cama A, Di Emidio P, Ferrari S, Perlangeli G, Rossi MB, Biglio A, De Riu G, Califano L, Vaira LA. Changes in hospital admissions for facial fractures during and after COVID 19 pandemic: national multicentric epidemiological analysis on 2938 patients. Oral Maxillofac Surg. 2023. Doi: 10.1007/s10006-023-01201-2. (Last author)


    184. Troise S, Committeri U, Barone S, Palumbo D, D’Auria D, Arena A, Romano A, Salzano G, Abbate V, Raccampo L, Sembronio S, Vaira LA, Dell’Aversana Orabona G, Califano L, Piombino P. Submental intubation in complex maxillofacial trauma: a new technique of pilot balloon protection and a narrative review of recent literature. J Craniomaxillofac Surg. 2023. Doi: 10.1016/j.jcms.2023.12.003.


    185. Maniaci A, Chiesa Estomba C, Fakhry N, Vaira LA, Remacle M, Cammaroto G, Barillari MR, Iannella G, Mayo-Yanez M, Saibene AM, Baudouin R, Maza-Solano J, Mendelson AH, Holsinger FC, Ceccon FP, Haddad L, Hans S, La Mantia I, Cocuzza S, Gulinello F, Ayad T, Lechien JR. Influence of Otolaryngological Subspecialties on Perception of Transoral Robotic Surgery: An International YO-IFOS Survey. J Pers Med. 2023;13:1717. 


    186. Saibene AM, Allevi F, Calvo-Henriquez C, Maniaci A, Mayo Yanez M, Paderno A, Vaira LA, Felisati G, Craig JR. Reliability of large language models in managing odontogenic sinusitis clinical scenarios: a preliminary multidisciplinary evaluation. Eur Arch Otorhinolryngol. 2024. Doi: 10.1007/s00405-023-08372-4.


    187. Lechien JR, Briganti G, Vaira LA. Accuracy of ChatGPT-3.5 and -4 in providing scientific references in otolaryngology-head and neck surgery. Eur Arch Otolaryngol. 2024. Doi: 10.1007/s00405-023-98441-8. (Last author)


    188. Lechien JR, Maniaci A, Gengler IM, Barillari MR, Vaira LA, Mayo-Yanez M. Acute or persistent mechanisms of dysphonia in COVID-19 patients. Am J Otolaryngol. 2024;45:104223.


    189. Vaira LA, Biglio A, Favro A, Salzano G, Abbate V, Lechien JR, De Riu G. Implant-prosthetic rehabilitation of the atrophic posterior mandible with additively manufactured custom-made subperiosteal implants: a cohort study. Int J Oral Maxillofac Surg. 2024. Doi: 10.1016/j.ijom.2024.01.003. (First author, corresponding author)


    190. Radulesco T, Saibene AM, Michel J, Vaira LA, Lechien JR. Chat-GPT4 performance in rhinology: a clinical case series. Int Forum Allergy Rhinol. 2024. Doi: 10.1002/alr.23323.


    191. Lechien JR, Vaira LA, Carsuzaa F, Lisan Q, Saussez S. Personalized medicine in olfactory testing: perspectives to improve patient compliance to psychophysical tests. Eur Arch Otorhinolaryngol. 2024. Doi: 10.1007/s00405-024-08454-x.


    192. Maniaci A, Saibene AM, Calvo-Henriquez C, Vaira L, Radulesco T, Michel J, Chiesa-Estomba C, Sowerby L, Lobo Duro D, Mayo-Yanez M, Maza-Solano J, Lechien JR, La Mantia I, Cocuzza S. Is generative pre-trained transformer artificial intelligence (Chat-GPT) a reliable tool for guidelines synthesis? A preliminary evaluation for biologic CRSwNP therapy. Eur Arch Otorhinolaryngol. 2024. Doi: 10.1007/s00405-024-08464-9. 


    193. Maniaci A, Vaira LA, Cammaroto G, Favier V, Lechien JR. Gastroesophageal reflux disease, laryngopharyngeal reflux, and nasopharyngeal reflux in chronic rhinosinusitis patients. Eur Arch Otorhinolaryngol. 2024. Doi: 10.1007/s00405-024-08510-6. 


    194. Maniaci A, Lechien JR, Vaira LA, La Via L. Taste and smell disorders: a critical look at olfactory and gustatory dysfunction. Life. 2024. Doi: 10.3390/life14030301.


    195. Vaira LA, Tirelli G, Rizzo D, Uderzo F, Avanzini F, Trabalzioni F, Rivelli N, Burger D, Calabrese L, Solla P, Bussu F, Mayo-Yanez M, Lechien JR, De Riu G, Boscolo-Rizzo P. Validity and reliability of the questionnaire of olfactory disorders for Italian-speaking patients with olfactory dysfunction. Acta Oto Ita. 2024;44:42-51. (First author, corresponding author)


    196. Salzano G, Audino G, Dell’Aversana Orabona G, Committeri U, Troise S, Arena A, Vaira LA, De Luca P, Scarpa A, Elefante A, Romano A, Califano L, Piombino P. Fresh frozen homologous rib cartilage: A narrative review of a new trend in rhinoplasty. J Clin Med. 2024;13(6):1715.


    197. Petrocelli M, Ruggiero F, Feraboli L, Allegri D, Cutrupi S, Baietti AM, Salzano G, Prucher G, Maremonti P. Vaira LA. The Evolution of the Epidemiology of Facial Fractures Before, During and After the COVID-19 Pandemic. J Maxillofac Oral Surg. 2024. Doi:  10.1007/s12663-024-02153-0. (Last author).


    198. Maniaci A, Lavalle S, Masiello E, Lechien JR, Vaira L, Boscolo-Rizzo P, Musa M, Gagliano C, Zeppieri M. Platelet-Rich Plasma (PRP) in the Treatment of Long COVID Olfactory Disorders: A Comprehensive Review. Biomedicines. 2024; 12(4):808. 


    199. Lechien JR, Naunheim MR, Maniaci A, Radulesco T, Saibene AM, Chiesa-Estomba CM, Vaira LA. Performance and consistency of ChatGPT-4 versus otolaryngologists: a clinical case series. Otolaryngol Head Neck Surg. 2024. Doi: 10.1002/ohn.759. (Last author).


    200. Mayo-Yáñez M, González-Torres L, Saibene A, Allevi F, Vaira LA, Maniaci A, Chiesa-Estomba CM, Lechien JR. Application of ChatGPT as a support tool in the diagnosis and management of acute bacterial tonsillitis. Health Technol. 2024. Doi: 10.1007/s12553-024-00858-3.


    201. Mayo-Yanez M, Lechien JR, Saibene AM, Vaira LA, Maniaci A, Chiesa-Estomba CM. Examining the performance of ChatGPT 3.5 and Microsoft Copilot in Otolaryngology: a comparative study with otolaryngologists’ evaluation. Indian J Otolaryngol Head Neck Surg. 2024. Doi: 10.1007/s12070-024-04729-1


    202. Vaira LA, Lechien JR, Abbate V, Allevi F, Audino G, Beltramini GA, Bergonzani M, Boscolo-Rizzo P, Califano G, Cammaroto G, Chiesa-Estomba CM, Committeri U, Crimi S, Curran NR, di Bello F, di Stadio A, Frosolini A, Gabriele G, Gengler IM, Lonardi F, Maglitto F, Mayo-Yáñez M, Petrocelli M, Pucci R, Saibene AM, Saponaro G, Tel A, Trabalzini F, Trecca EMC, Vellone V, Salzano G, De Riu G. Validation of the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool: a new tool to assess the quality of health information provided by AI platforms. Eur Arch Otorhinolaryngol. 2024. Doi: 10.1007/s00405-024-08710-0. (First author, corresponding author).


    203. Lorenzi A, Pugliese G, Maniaci A, Lechien JR, Allevi F, Boscolo-Rizzo P, Vaira LA, Saibene AM. Reliability of large language models for advanced head and neck malignancies management: a comparison between ChatGPT4 and Gemini Advanced. Eur Arch Otorhinolaryngol. 2024. Doi: 10.1007/s00405-024-08746-2. (Co-senior author).


    204. Lechien JR, Hmdan AL, Fakhry N, Vaira LA, Iannella G, Gengler IM, Michel J, Radulesco T, Remacle M, Hans S, Cammaroto G, Saibene AM, Mayo-Yanez M, Maniaci A. Perception of Young European Otolaryngologists toward transoral robotic surgery in head and neck oncology and surgery. J Clin Med. 2024;13:3055.


    205. Vaira LA, Biglio A, Roy M, Salzano G, Troise S, Abbate V, Mayo-Yanez M, Lechien JR, Piombino P, De Riu G. Full-arch rehabilitation of severely atrophic maxilla with additively manufactured custom-made subperiosteal implants: a multicenter retrospective study. J Craniomaxillofac Surg. 2024. Doi: 10.1016/j.jcms.2024.06.016. (First author, corresponding author).


    206. De Vito A, Geremia N, Marino A, Bavaro DF, Caruana G, Meschiari M, Colpani A, Mazzitelli M, Scaglione V, Venanzi Rullo E, Fiore V, Fois M, Campanella E, Pistarà E, Faltoni M, Nunnari G, Cattelan A, Mussini C, Bartoletti M, Vaira LA, Madeddu G. Assessing ChatGPT's theoretical knowledge and prescriptive accuracy in bacterial infections: a comparative study with infectious diseases residents and specialists. Infection. 2024 doi: 10.1007/s15010-024-02350-6. 


    207. Vaira LA, Biglio A, Salzano G, Lechien JR, De Riu G. Additively manufactured custom-made subperiosteal implant rehabilitation for severely atrophic maxillary molar area: A technical note. J Stomatol Oral Maxillofac Surg. 2024. doi: 10.1016/j.jormas.2024.101917. 


    208. Dell'Aversana Orabona G, Abbate V, De Fazio GR, Calvanese C, Vaira L, Bonavolontà P, Romano A, Improta G, Piombino P, Califano L. Effects of serial swabs on the nasopharyngeal mucosa: our experience in SARS-CoV2 screening. J Infect Dev Ctries. 2024;18:987-992.


    209. Troise S, Carraturo E, Committeri U, Barone S, Norino G, De Riu G, Vaira LA, Abbate V, Mariniello D, Califano L, Piombino P. Epidemiological analysis of the facial fractures pattern in relation to motorcycle helmet type: a retrospective study on 282 patients. J Craniomaxillofac Surg. 2024. Doi: 10.1016/j.jcms.2024.03.013.


    210. Carraturo E, Germano C, Troise S, Spinelli R, Romano A; Lo Giudice G, Vaira LA, Piombino P.  In house 3-D printed surgical Guide for frontal sinus osteotomy in traumatology: a technical note. J Stomatol Oral Maxillofac Surg. 2024. Doi: 10.1016/j.jormas.2024.102023. 


    211. Troise S, De Fazio GR, Committeri U, Spinelli R, Nocera M, Carraturo E, Salzano G, Arena A, Abbate V, Bonavolontà P, Romano A, Orabona GD, Vaira LA, Piombino P. Mandibular reconstruction after post-traumatic complex fracture: comparison analysis between traditional and virtually planned surgery. J Stomatol Oral Maxillofac Surg. 2024. Doi: 10.1016/j.jotmas.2024.102029.


    212. Salzano G, Maffia F, Vaira LA, Fusco R, Albanese M, Crimi S, Cucurullo M, Maglitto F, Maugeri C, Petrocelli M, Pitino F, Priore P, Roccia F, Tel A, Baietti AM, Bianchi A, Biglioli F, Copelli C, De Riu G, Nocini PF, Ramieri G, Robiony M, Valentini V, Califano L. The impact of standing electric scooters on maxillofacial fractures: an Italian multi-centric epidemiological study. J Clin Med. 2024;13:5195.


    213. Chiesa-Estomba CM, Mayo-Yanez M, Vaira LA, Maniaci A, Feng AL, Landa-Garmendia M, Cardin-Pereda A, Lechien JR. Oral cavity cancer secondary to dental trauma: a scoping review. Biomedicines 2024;12:2024.


    214. Vaira, LA, De Riu G, Maniaci A, Mayo-Yáñez M, Saibene AM, Chiesa-Estomba CM, Lechien JR. In Reference to Impact of Nutritional Status on COVID-19-Induced Olfactory Dysfunction. The Laryngoscope. 2024, Doi: 10.1002/lary.31745.


    215. Salzano G, Barone S, De Luca P, Borriello G, Vaira LA, Troise S, Granata V, Committeri U, Perri F, Esposito M, di Basi F, Petrocelli M, Ionna F, Califano L, Dell’Aversana Orabona G, Di Stadio A. Predictive value of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and systemic inflammatory index for detection of recurrence of pleomorphic adenoma of the major salivary glands. A multicenter study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2024. Doi: 10.1016/j.000.2024.08.014.


    216. Khaldi A, Machayekhi S, Salvagno M, Maniaci A, Vaira LA, La Via L, Taccone FS, Lechien JR. Accuracy of ChatGPT responses on tracheotomy for patient education. Eur Arch Otorhinolaryngol. 2024. Doi:10.1007/s00405-024-08859-8. 


    217. Lechien JR, Mayo-Yanez M, Chiesa-Estomba CM, et al. Association between empty nose syndrome and laryngopharyngeal reflux disease: a preliminary cohort study. Eur Arch Otorhinolaryngol. 2024. doi:10.1007/s00405-024-09019-8


    218. Vaira LA, Lechien JR, Maniaci A, Tanda G, Abbate V, Allevi F, Arena A, Beltramini GA, Bergonzani M, Bolzoni AR, Crimi S, Frosolini A, Gabriele G, Maglitto F, Mayo-Yanez M, Orrù L, Petrocelli M, Pucci R, Saibene AM, Troise S, Tel A, Vellone V, Chiesa-Estomba CM, Boscolo-Rizzo P, Salzano G, De Riu G. Evaluating AI-generated informed consent documents in oral surgery: a comparative study of ChatGPT-4, Bard gemini advanced, and human-written consents. J Craniomaxillofac Surg. 2024. Doi: 10.1016/j.jcms.2024.10.10.002. (First author, corresponding author).


    219. Iannella G, Pace A, Greco A, De Virgilio A, Gatti L, Maniaci A, Lechien JR, Hervochon R, Faramarzi A, Mat Q, Cherkes M, Koiner-Graupp M, Boscolo-Rizzo P, Vaira LA, Magliulo G. Endoscopic versus microscopic approach in the treatment of atelectatic otitis media. Acta Otolaryngol. 2024 Nov 25:1-10. doi: 10.1080/00016489.2024.2424947.


    220. Lechien JR, Vaira LA, Georgescu BM, Maniaci A, Hans S, Saussez S. Recovery of misattributed congenital anosmia after platelet-rich plasma injections: Report of two cases. Braz J Otorhinolaryngol. 2024 Nov 27;91(2):101538. Doi: 10.1016/j.bjorl.2024.101538. 


    221. Boscolo-Rizzo P, Marcuzzo AV, Lazzarin C, Giudici F, Polesel J, Stellin M, Pettorelli A, Spinato G, Ottaviano G, Ferrari M, Borsetto D, Zucchini S, Trabalzini F, Sia E, Gardenal N, Baruca R, Fortunati A, Vaira LA, Tirelli G. Quality of Information Provided by Artificial Intelligence Chatbots Surrounding the Reconstructive Surgery for Head and Neck Cancer: A Comparative Analysis Between ChatGPT4 and Claude2. Clin Otolaryngol. 2024. doi: 10.1111/coa.14261. 


    222. Lachien JR, Aoun J, Iannella G, Maniaci A, Vaira LA. In reference to scintigraphic imaging of extra-esophageal manifestation of gastroesophageal reflux disease. Laryngoscope. 2024. Doi: 10.1002/lary.31884.


    223. Committeri U, Magliulo R, Carraturo E, Arena A, Abbate V, Salzano G, Troise S, Barone S, Germano C, Vaira LA, Giovacchini F, Cataldo R, Grassia MG, Califano L, Piombino P. Virtual surgical planning in tripod zygomatico-maxillary complex fractures: A prospective comparison between two different strategies. J Craniomaxillofac Surg. 2024 Doi: 10.1016/j.jcms.2024.08.020.


    224. Vaira LA, De Riu G, Chiesa-Estomba CM, Maniaci A, Mayo-Yanez M, Saibene AM, Lechien JR. How we ask matters: ensuring accurate responses from AI in patient counseling. Am J Otolaryngol. 2024. Doi: 10.1016/j.amjoto.2024.104557.


    225. Lechien JR, Chiesa-Estomba CM, Hans S, Nacci A, Schindler A, Bohlender JE, Runggaldier D, Crevier-Buchman L, Oguz H, Zelenik K, Tedla M, Siupsinskiene N, Schlömicher-Thier J, Taimrova R, Karkos PD, Geneid A, Dapri G, Aoun J, Muls V, Weitzendorfer M, Savarino EV, Remacle MJ, Sereg-Bahar M, Mayo-Yanez M, Iannella G, Saibene AM, Vaira LA, Cammaroto G, Maniaci A, Barillari MR. European clinical practice guideline: managing and treating laryngopharyngeal reflux disease. Eur Arch Otorhinolaryngol. 2024 Dec 24. doi: 10.1007/s00405-024-09181-z.


    226. Vaira LA, Lechien JR, Abbate V, Gabriele G, Frosolini A, De Vito A, Maniaci A, Mayo-Yáñez M, Boscolo-Rizzo P, Saibene AM, Maglitto F, Salzano G, Califano G, Troise S, Chiesa-Estomba CM, De Riu G. Enhancing AI Chatbot Responses in Health Care: The SMART Prompt Structure in Head and Neck Surgery. OTO Open. 2025 Jan 16;9(1):e70075. (First author, corresponding author).


    227. Di Bello F, Califano G, Collà Ruvolo C, Morra S, Fraia A, Mocini E, Muzii B, Napolitano L, Creta M, Salzano G, Vaira LA, Mangiapia F, Maldonato NM, Cantone E, Longo N. Erectile dysfunction and obstructive sleep apnea syndrome: a post-hoc evaluation of Italian survey results. Minerva Urol Nephrol. 2025 Feb 5. doi: 10.23736/S2724-6051.24.05925-1. 


    228. Lechien JR, Ragrag K, Kasongo J, Favier V, Mayo-Yanez M, Chiesa-Estomba CM, Iannella G, Cammaroto G, Saibene AM, Vaira LA, Carsuzaa F, Sagandykova K, Fieux M, Lisan Q, Hans S, Maniaci A. Association between Helicobacter pylori, reflux and chronic rhinosinusitis: a systematic review. Eur Arch Otorhinolaryngol. 2025 Feb 2. doi: 10.1007/s00405-025-09212-3. Epub ahead of print.


    229. Lechien JR, Maniaci A, Kipsang MJ, Kibor M, Vaira LA. High-definition otoscopic device for humanitarian mission: how i do it. Eur Arch Otorhinolaryngol. 2025 Feb 1. doi: 10.1007/s00405-025-09219-w. 


    230. Roy M, Cerea M, Hedzelek W, Vaira LA, Dorocka-Bobkowska B. Additively Manufactured Subperiosteal Implants for the Rehabilitations of Lateral Incisors Agenesis - a case series. J Stomatol Oral Maxillofac Surg. 2025 Jan 25:102263. doi: 10.1016/j.jormas.2025.102263. Epub ahead of print. (Corresponding author) 


    231. Vaira LA, De Riu G, Maniaci A, Mayo-Yáñez M, Saibene AM, Chiesa-Estomba CM, Lechien JR. In Reference to Utilization of Artificial Intelligence in the Creation of Patient Information on Laryngology Topics. Laryngoscope. 2025 Feb 11. doi: 10.1002/lary.32032.(First author, corresponding author)


    232. Cirignaco G, Monarchi G, Betti E, Paglianiti M, Catarzi L, Tel A, Vaira LA, Balercia P, Consorti G. Outcome of Facial Nerve Integrity After Parotid Gland Surgery With and Without Intraoperative Monitoring: A Ten-Year Retrospective Study. Journal of Clinical Medicine. 2025; 14(4):1156.


    233. Perrotta S, Carraturo E, D'Antò V, Ludwig B, Bocchino T, Vaira LA, De Riu G, Valletta R, Piombino P. A Novel Virtual Planned-Orthodontic-Surgical Approach for Proportional Condylectomy in Condylar Hyperplasia. J Clin Med. 2025 Jan 24;14(3):752. doi: 10.3390/jcm14030752. 


    234. Borsetto D, Sia E, Axon P, Donnelly N, Tysome JR, Anschuetz L, Bernardeschi D, Capriotti V, Caye-Thomasen P, West NC, Erbele ID, Franchella S, Gatto A, Hess-Erga J, Kunst HPM, Marinelli JP, Mannion R, Panizza B, Trabalzini F, Obholzer R, Vaira LA, Polesel J, Giudici F, Carlson ML, Tirelli G, Boscolo-Rizzo P. Quality of Information Provided by Artificial Intelligence Chatbots Surrounding the Management of Vestibular Schwannomas: A Comparative Analysis Between ChatGPT-4 and Claude 2. Otol Neurotol. 2025 Feb 4. doi: 10.1097/MAO.0000000000004410. 


    235. Vaira LA, Biglio A, Salzano G, Pispero A, Lechien JR, De Riu G. Custom fabricated subperiosteal implants for sectional rehabilitation of severely atrophic maxillae: a technical note. J Oral Maxillofac Surg. 2025. Doi: 10.1016/j.joms.2025.02.007. (First author, corresponding author).


    236. Maniaci A, Gagliano C, Salerno V, Cilia N, Lavalle S, Saibene AM, Cammaroto G, Chiesa-Estomba C, Radulesco T, Vaira L, Iannella G, Fakhry N, Lechien JR. ChatGPT 4.0 and algor in generating concept maps: an observational study. Eur Arch Otorhinolaryngol. 2025 Feb 20. doi: 10.1007/s00405-025-09255-6. 


    237. Chiesa-Estomba CM, Maniaci A, Vaira LA, Lechien JR. Leveraging artificial intelligence in next generation sequencing for head & neck cancer: opportunities and challenges. Eur Arch Otorhinolaryngol. 2025 Mar 1. doi: 10.1007/s00405-025-09256-5. 


    238. Zeroual M, Ginatempo F, Loi N, Vaira LA, Cano A, Biglio A, Visaloco G, De Riu G, Deriu F. Sensorimotor integration and faces recognition in a model of altered face sensory information: neurophysiological study in patients with dentofacial deformities. Clin Neurophysiol. 2025;173:113-123.


    239. Vaira LA, Massarelli O, Polesel J, Ferri A, Chiesa-Estomba CM, Cuéllar IN, Consorti G, Cirignaco G, Cucurullo M, Salzano G, Padmanabhan S, George A, Petrocelli M, Ali J, González-Garcia JA, Manfuso A, Ayad T, Cuéllar CN, Giudici F, Lechien JR, Joseph ST, Copelli C, Biglioli F, Ferrari S, De Riu G. Oncologic Safety of Facial-Vessel-Based Buccinator Myomucosal Flaps for Tongue and Oral Floor Reconstruction: A Retrospective Multicenter Case-Control Study. Head Neck. 2026 Mar;48(3):827-836. doi: 10.1002/hed.70082. (First author, corresponding author)


    240. De Vito A, Geremia N, Bavaro DF, Seo SK, Laracy J, Mazzitelli M, Marino A, Maraolo AE, Russo A, Colpani A, Bartoletti M, Cattelan AM, Mussini C, Parisi SG, Vaira LA, Nunnari G, Madeddu G. Comparing Large Language Models for antibiotic prescribing in different clinical scenarios: which perform better? Clin Microbiol Infect. 2025. doi: 10.1016/j.cmi.2025.03.002. 


    241. Chiesa-Estomba CM, Andueza-Guembe M, Maniaci A, Mayo-Yanez M, Betances-Reinoso F, Vaira LA, Saibene AM, Lechien JR. Accuracy of ChatGPT-4o in Text and Video Analysis of Laryngeal Malignant and Premalignant Diseases. J Voice. 2025 Mar 26:S0892-1997(25)00100-6. doi: 10.1016/j.jvoice.2025.03.006. 


    242. Lechien JR, Chiesa-Estomba CM, Hans S, Nacci A, Schindler A, Bohlender JE, Runggaldier D, Crevier-Buchman L, Oguz H, Zelenik K, Tedla M, Siupsinskiene N, Schlömicher-Thier J, Taimrova R, Karkos PD, Geneid A, Dapri G, Aoun J, Muls V, Weitzendorfer M, Savarino EV, Remacle MJ, Sereg-Bahar M, Mayo-Yanez M, Iannella G, Saibene AM, Vaira LA, Cammaroto G, Maniaci A, Barillari MR. Correction: European clinical practice guideline: managing and treating laryngopharyngeal reflux disease. Eur Arch Otorhinolaryngol. 2025 Mar 27. doi: 10.1007/s00405-025-09307-x. Epub ahead of print. Erratum for: Eur Arch Otorhinolaryngol. 


    243. Troise S, Carraturo E, Napolitano R, Merola R, Vaira LA, Abbate V, Romano A, Bonavolontà P, Raccampo L, Sembronio S, Robiony M, De Riu G, Piombino P. Surgical approaches for bilateral Eagle’s syndrome: a narrative review of literature. Curr Probl Surg. 2025. Doi: 10.1016/j.cpsurg.2025.101765.


    244. Spallaccia F, De Tomaso S, Cirignaco G, Angelo DF, Vaira LA, Vellone V. Temporo-mandibular joint functional arthroplasty: does it improve the short-term quality of life in patients with painful anterior disc displacement without reduction? A retrospective cohort study. J Clin Med. 2025;14:2560.


    245. De Riu G, Biglio A, Baj A, Maniaci A, Lechien JR, Vaira LA. Primary reconstruction of total maxillectomy defect with additively manufactured subperiosteal implant and fibula free flap: a case report. Oral Maxillofac Surg. 2025 Apr 21;29(1):86. doi: 10.1007/s10006-025-01379-7. 


    246. Melis M, Loi E, Aru G, Sollai G, Mastinu M, Naciri LC, De Riu G, Vaira LA, Costanzo G, Firinu D, Cabras P, Caddori A, Crnjar R, Zavattari P, Tomassini Barbarossa I. TAS2R38 gene methylation is associated with syndrome Coronavirus 2 (SARS-CoV-2) infection and clinical symptoms. Sci Rep. 2025 Apr 25;15(1):14462.


    247. Ottavi A, Cozzi A, Allevi F, Calvo-Henriquez C, Chiesa-Estomba C, Felisati G, Lechien JR, Maniaci A, Mayo-Yáñez M, Pecorari G, Riva G, Vaira LA, Saibene AM, Urbanelli A. Therapeutic management of traumatic facial palsy: a systematic review. Eur Arch Otorhinolaryngol. 2025 Apr 26. doi: 10.1007/s00405-025-09367-z. 


    248. Mantione G, Cavelier G, Rodriguez A, Dequanter D, Saussez S, Hans S, Maniaci A, Iannella G, Dapri G, Vaira L, Chiesa-Estomba CM, La Via L, Bonavina L, Lechien JR. Clinical Findings, Feasibility, and Patient Tolerance of Nasopharyngeal Dx-pH System for Detecting Nasopharyngeal Reflux Disease. J Voice. 2025 May 2:S0892-1997(25)00172-9. doi: 10.1016/j.jvoice.2025.04.023.


    249. De Vito A, Geremia N, Bavaro DF, Seo SK, Laracy J, Mazzitelli M, Marino A, Maraolo AE, Russo A, Colpani A, Bartoletti M, Cattelan AM, Mussini C, Parisi SG, Vaira LA, Nunnari G, Madeddu G. 'Comparing Large Language Models for antibiotic prescribing in different clinical scenarios' - Author's reply. Clin Microbiol Infect. 2025 May 7:S1198-743X(25)00224-1. doi: 10.1016/j.cmi.2025.04.041.


    250. Salzano G, Scocca V, Troise S, Abbate V, Bonavolontà P, Vaira LA, Scarpa A, Lechien JR, De Fazio G, Carraturo E, et al. Advancing Maxillary Reconstruction: A Systematic Review and Meta-Analysis of the Evolving Role of the Scapular Free Flap. Journal of Clinical Medicine. 2025; 14(10):3278. Doi: 10.3390/jcm14103278.


    251. Maniaci A, Lentini M, Vaira L, Lavalle S, Ronsivalle S, Rubulotta FM, Lentini L, Paternò DS, Galletti C, Sorbello M, et al. The Global Burden of Maxillofacial Trauma in Critical Care: A Narrative Review of Epidemiology, Prevention, Economics, and Outcomes. Medicina. 2025; 61(5):915. Doi: 10.3390/medicina61050915


    252. Lechien JR, Saxena S, Vaira LA, Hans S, Maniaci A. Artificial Intelligence-Assisted Diagnosis of an Unusual Cause of Periodic Epistaxis: A Case Report. Ear Nose Throat J. 2025 Jun 3:1455613251335385. doi: 10.1177/01455613251335385.


    253. Maniaci A, Salzano G, Vaira LA, Chiesa-Estomba CM, Lechien JR. In Reference to "The Prevalence of Local Symptoms in Benign Thyroid Disease: A Systematic Review With Meta-Analysis". Laryngoscope. 2025 May 27. doi: 10.1002/lary.32298. 


    254. Chiesa-Estomba CM, Andueza-Guembe M, Maniaci A, Mayo-Yanez M, Vaira LA, Lechien JR. In Reference to the Evolution of Multidisciplinary Head and Neck Cancer Treatment. Laryngoscope. 2025 Jun 10. doi: 10.1002/lary.32309. 


    255. De Riu G, Biglio A, Spano G, Consorti G, Lechien JR, Vaira LA. Implant-Prosthetic Rehabilitation of a Patient With EEC Syndrome Using Additively Manufactured Custom-Made Subperiosteal Implants: A Case Report. Cleft Palate Craniofac J. 2025 Jun 16:10556656251350443. (Last author, corresponding author).


    256. Cirignaco G, Catarzi L, Monarchi G, Petrocelli M, Committeri U, Troise S, Tel A, Vaira LA, Consorti G. Timing of dietary progression after mandibular fracture repair: the role of comorbidities and their impact on postoperative outcomes. Ann Chir. 2025. Doi: https://annaliitalianidichirurgia.it/index.php/aic/article/view/4006


    257. Lechien JR, Salzano G, Vaira L, Maniaci A, Barillari MR. Letter to the Editor on "The Role of Sucralfate in Post-Tonsillectomy Pain in Children: A Scoping Review". Ann Otol Rhinol Laryngol. 2025 Jun 30:34894251351855. 


    258. Mayo-Yáñez M, Rameau A, Vaira LA, Louvrier M, Sanchez Barrueco A, Alcalá-Rueda I, García-Curdi F, Mejuto-Torreiro L, Klein-Rodríguez A, Herranz-Larrañeta J, Maza-Solano J, Saibene AM, Pugliese G, Briganti G, Chiesa-Estomba CM, Simon F, Hans S, Baudouin R, Rodriguez A, Dequanter D, Saussez S, Radulesco T, Michel J, Gengler IM, Naunheim MR, Cammaroto G, De Vito A, Iannella G, Favier V, Carsuzaa F, Barillari MR, Maniaci A, Lechien JR. Patient Perceptions of Artificial Intelligence in Otolaryngology-Head and Neck Surgery: An International Study. Ear Nose Throat J. 2025 Jun 28:1455613251351774. doi: 10.1177/01455613251351774.


    259. Boscolo-Rizzo P, Tagliabue M, Polesel J, Giudici F, Rampinelli V, Spinato G, Vaira LA, Golusinski P, Dequanter D, Chiesa Estomba C, Maniaci A, Lentini M, De Berardinis R, Iandolo L, Borsetto D, Szewczyk M, Bussu F, Lechien JR, Emanuelli E, Piazza C, Nicolai P, Ansarin M, Tirelli G. HPV Status and Survival Outcomes in Patients 70 Years and Older After Surgery for Oropharyngeal Carcinoma. JAMA Otolaryngol Head Neck Surg. 2025 Jul 3. doi: 10.1001/jamaoto.2025.1722. 


    260. Lechien JR, Hamdan AL, Maniaci A, Mayo-Yanez M, Cammaroto G, Kan K, Barillari MR, Calvo-Henriquez C, Hans S, Radulesco T, Fakhry N, Michel J, Saibene AM, Chiesa-Estomba CM, Iannella G, Briganti G, Karkos PD, Ayad T, Boscolo-Rizzo P, Vaira LA, Meço C, Tedla M, Plzak J, Remacle M, Sims HS. Gender-Related Discriminations in European Otolaryngology-Head and Neck Surgery: European Report. Surg Innov. 2025 Jul 15:15533506251361569. doi: 10.1177/15533506251361569. 


    261. Radulesco T, Ebode D, Maniaci A, Gargula S, Saibene AM, Chiesa-Estomba C, Gengler I, Vaira L, Vishnumurthy P, Lechien JR, Michel J. Evaluation of Artificial Intelligence Chatbots for Facial Injection Planning: Comparative Performance and Safety Limitations. Aesthetic Plast Surg. 2025 Jul 16. doi: 10.1007/s00266-025-05010-8.


    262. De Riu G, Mommaerts MY, Soma D, Biglio A, Roy M, Troise S, Maniaci A, Lechien JR, Vaira LA. Three-dimensionally printed subperiosteal implants for maxillectomy reconstruction: report of nine cases. Int J Oral Maxillofac Surg. 2025 Jul 18:S0901-5027(25)01372-4. doi: 10.1016/j.ijom.2025.07.001. 


    263. Boscolo-Rizzo P, Spinato G, De Colle R, Maniaci A, Vaira LA, Emanuelli E, Tirelli G. Five-Year Longitudinal Assessment of Self-reported COVID-19-Related Chemosensory Dysfunction. Clin Infect Dis. 2025 Jul 23:ciaf331. doi: 10.1093/cid/ciaf331.


    264. Boscolo-Rizzo P, Hummel T, Marcuzzo AV, Maniaci A, Spinato G, Raimondo L, Vaira LA, Tulissi R, Menini A, Trabalzini F, Emanuelli E, Grill V, Polesel J, Giudici F, Tirelli G. Effects of smoking cessation on taste function in heavy smokers undergoing hemiglossectomy for tongue squamous cell carcinoma. Eur Arch Otorhinolaryngol. 2025 Jul 23. doi: 10.1007/s00405-025-09590-8. 


    265. Vaira LA, Lechien JR, Maniaci A, De Vito A, Mayo-Yáñez M, Troise S, Consorti G, Chiesa-Estomba CM, Cammaroto G, Radulesco T, et al. Diagnostic Performance of ChatGPT-4o in Analyzing Oral Mucosal Lesions: A Comparative Study with Experts. Medicina. 2025; 61(8):1379. (First author, corresponding author).


    266. Salzano G, Scocca V, Troise S, Abbate V, Bonavolontà P, Vaira LA, Committeri U, Lechien JR, Tramontano S, Canterino V, et al. Pleomorphic Adenoma: Extracapsular Dissection vs. Superficial Parotidectomy—An Updated Systematic Review and Meta-Analysis. Medical Sciences. 2025; 13(3):104.


    267. Benedetti S, Frosolini A, Catarzi L, Vaira LA, Consorti G, Paglianiti M, Gennaro P, Gabriele G. Large Language Models and Surgical Decision-Making: Evaluation of Generative Unimodal AI in Facial Traumatology Practice. J Maxillofac Oral Surg. 2025. Doi: 10.1007/s12663-025-02556-7.


    268. Bahgat A, Elwany M, Vicini C, et al. Effect of targeted multilevel sleep surgery on resistant hypertension in patients with severe obstructive sleep apnea. J Int Med Res. 2025;53(9):3000605251361484.


    269. Salzano G, Scocca V, Committeri U, et al. Parotid gland sialolithiasis: a comprehensive systematic review and meta-analysis : Title page. Eur Arch Otorhinolaryngol. 2025. doi:10.1007/s00405-025-09697-y.


    270. Segna E, Bolzoni AR, Montan F, Vaira LA, Beltramini GA. One-step primary complete rehabilitation following maxillectomy for a benign tumor: advancements in midface recontruction. J Prost Dent. 2025. Doi: j.prosdent.2025.08.048.


    271. Consorti G, De Tomaso S, Monarchi G, Paglianiti M, Vaira LA, Betti E, Caterzi L. Management of post-traumatic silent sinus syndrome with patient-specific implant. J Oral Maxillofac Surg Med Pathol. 2025. Doi: 10.1016/j.ajoms.2025.10.008.


    272. Cammaroto G, Mira FA, Favier V, Nunes HDSS, de Castro JV, Carsuzaa F, Lechien JR, Chiesa Estomba C, Iannella G, Vaira LA, Calvo-Henriquez C, Cheong RCT, de Apodaca PMR, Lentini M, Barillari MR, Maniaci A. Experts V/S AI´s 2.0: Comparative evaluation of AI models and expert consensus in obstructive sleep apnea assessment. Eur Arch Otorhinolaryngol. 2025 Nov 1. doi: 10.1007/s00405-025-09785-z. 


    273. Cirignaco G, Rosettani P, Catarzi L, Paglianiti M, Betti E, Committeri U, Vaira LA, Santarelli A, Consorti G. Surgical site infections in oral cavity carcinoma: predictive factors, microbiological trends, and clinical implications – experience of a major italian medical center. Oral Surg Oral Med Oral Pathol Radiol. 2025. Doi:  10.1016/j.oooo.2025.10.012


    274. Salzano G, Scocca V, Romano A, Vaira LA, Lechien JR, Maglitto F, Petrocelli M, Dell’Aversana Orabona G. Surgical outcomes and complications of distal nasal recontruction: a systematic review and meta-analysis. J Clin Med. 2025,14:7983


    275. Iannella G, Terranova S, Brunori M, Vicini C, Caranti A, Campisi R, De Cegli V, Casale M, Moffa A, Salamanca F, Leone F, De Vito A,Cammaroto G, Cocuzza S, Maniaci A, De Virgilio A, Lechien JR, Chiesa-Estomba CM, Vaira LA, Boscolo Rizzo P, Pace A. Effectiveness of drug-induced sleep endoscopy in improving patients selection and outcomes of mandibular advancement device therapy for obstructive sleep apnea: A multicenter case-control study. Am J Otolaryngol. 2025. Doi: 10.1016/j.amjoto.2025.104740.


    276. Lechien JR, Vaira LA, Lamoulen L, et al. Validity and Reliability of the French Olfactory Disorders Questionnaire-10. J Otolaryngol Head Neck Surg. 2025;54:19160216251387622. doi:10.1177/19160216251387622.


    277. Laganà F, Brevi BC, Marzi Manfroni A, Arcuri F, Spinzia A, Ardito E, Vaira LA, Sako M, Papa EB, Bianchi B. Mandibular ramus vertical augmentation in hemifacial microsomia: technical evolution from osteogenic distraction to sagittal osteotomy. Surg Tech Dev. 2024,14:40.


    278. Abbate V, Carraturo E, Benfanatic D, Tramontano S, Vaira LA, Troise S, Canzi G, Novelli F, Pacella D, Russo C, Tommasino C, Nocini R, Rinaldi AM, Dell’aversana Orabona G. Text-guided inpanting for aesthetic prediction in orthofacial surgery: a patient-centered AI approach. Medicina. 2025, 61:2075


    279. Vaira LA, Salzano G, Navarro-Cuéllar C, Maniaci A, Lechien JR, De Riu G. Comment on: "Patient-Specific Cranio-Facial Porous Titanium Implants: A Multicentric Cohort Study". Head Neck. 2025. doi:10.1002/hed.70115 (First author, Corresponding author).


    280. Lechien JR, Lazzeroni M, Salzano G, Vaira LA, Maniaci A, Hamdan AL. In Reference to The Role of Hypoalbuminemia in the Development of Reinke's Edema: A Prospective Cohort Study. Laryngoscope. 2025. doi:10.1002/lary.70339


    281. Vaira LA, Micheluzzi V, Lechien JR, Maniaci A, Maglitto F, Cammaroto G, Troise S, Chiesa-Estomba CM, Consorti G, Cirignaco G, et al. Telemedicine in Oral and Maxillofacial Surgery: A Narrative Review of Clinical Applications, Outcomes and Future Directions. Journal of Clinical Medicine. 2026; 15(2):452. (First author, Corresponding author).


    282. Maglitto F, Troise S, Calabria F, Trotta S, Salzano G, Vaira LA, Abbate V, Bonavolontà P, Dell’Aversana Orabona G. Complications of Free Flap Reconstruction in Maxillary and Mandibular Defects: A Systematic Review and Meta-Analysis. J Clin Med. 2026; 15(2):797.


    283. Troise S, Calabria F, Spinelli R, De Masi S, Tramontano S, Abbate V, Bonavolontà P, Salzano G, De Fazio GR, Romano A, Vaira LA, Consorti G, Cuellar CN, Orabona GD. Virtual surgical planning and 3D custom-made implants in the management of orbital floor fractures: a case control study. J Stomatol Oral Maxillofac Surg. 2026. doi: 10.1016/j.jormas.2026.102718. 


    284. Vaira LA, De Riu G, Salzano G, Chiesa-Estomba CM, Consorti G, Cirignaco G, et al. Validation of the QAMAI tool in Italian for the evaluation AI-generated health information in head and neck surgery. Otorhinolaryngology 2025;75:120-6. DOI: 10.23736/S2724-6302.25.02603-9 (First author, Corresponding author)


    285. Vaira LA, Biglio A, Maniaci A, Lechien JR, De Riu G. Comment on: “clinical behaviour and complications of CAD-CAM subperiosteal implants supporting fixed partial restorations: a scoping review. Br J Oral Maxillofac Surg 2026. Doi: j.bjoms.2026.01.011. (First author, Corresponding author).


    286. Lechien JR, Maniaci A, Salzano G, Chiesa-Estomba CM, Mayo-Yanez M, Saibene A, Iannella G, Saussez S, Vaira LA. Patient perception and awareness of psychophysical olfactory tests: A cross-sectional observational survey. Eur Ann Otorhinolaryngol Head Neck Dis 2026. Doi: 10.1016/j.anorl.2025.09.009. (Last author)


    287. Consorti G, Catarzi L, Frosolini A, Vaira LA, Committeri U, Cirignaco G. Artificial intelligence in oral and maxillofacial surgery: a scoping review of clinical applications, ethical challenges, and legal considerations. Int J Oral Maxillofac Surg. 2026. Doi: 10.1016/j.ijom.2026.02.020 


    288. Lechien JR, Vaira LA, Salzano G, Chiesa-Estomba CM, Maniaci A, Iannella G. In Reference to GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta-Analysis. Laryngoscope. 2026 Feb 20. doi: 10.1002/lary.70457. Epub ahead of print. PMID: 41717665.


    289. Maniaci A, Chiari F, Guarino P, La Via L, Lentini M, Lavalle S, Boscolo-Rizzo P, Vaira LA, Lechien JR. Global Burden of Deep Neck Space Abscesses: Epidemiology, Challenges, and Outcomes. Journal of Personalized Medicine. 2026; 16(3):146. https://doi.org/10.3390/jpm16030146


    290. González Moure B, Khayat S, Fernández Acosta D, Navarro Cuéllar I, Maza Muela C, López López A, Tousidonis Rial M, Arenas de Frutos G, Martínez Martínez C, Antúnez-Conde R, et al. Beyond Accuracy: Perioperative Efficiency and Institutional Cost Implications of CAD/CAM-Guided Versus Conventional Freehand Fibula Free Flap Reconstruction for Mandibular and Maxillary Defects. Journal of Clinical Medicine. 2026; 15(5):1778. 


    291. Cirignaco G, Paglianiti M, Catarzi L, Betti E, Monarchi G, Gilli M, Vaira LA, Consorti G. Patient satisfaction in orthognathic surgery and the role of expectations. J Craniomaxillofac Surg. 2026 Mar 9;54(6):104530. doi: 10.1016/j.jcms.2026.104530


    292. Vaira LA, Massarelli O, Biglio A, Salzano G, Maniaci A, Lechien JR, De Riu G. Craniofacial speargun injuries: report of three cases, literature review and proposed management guidelines for maxillo-facial surgeons. Oral Maxillofac Surg. 2026 Mar 11;30(1):51. doi: 10.1007/s10006-026-01534-8. (First author, Corresponding author).


    293. Vaira LA, Qadeer H, Lechien JR, Maniaci A, Maglitto F, Troise S, Chiesa-Estomba CM, Consorti G, Cirignaco G, Iannella G, et al. Safety-First Framework for AI-Enabled Anamnesis in Head and Neck Surgery: Evidence Synthesis from a Narrative Review. Journal of Clinical Medicine. 2026; 15(6):2218. (First author, Corresponding author).


    294. Cirignaco G, Lo Giudice G, Caso AR, Gasperoni M, Clementi S, Gentili L, Messi M, Troise S, Vaira LA, Lo Giudice R, et al. Sedation and General Anesthesia in Non-Cooperative Dental Patients: An Italian Clinical Experience. Journal of Clinical Medicine. 2026; 15(7):2532. https://doi.org/10.3390/jcm15072532


    295. Vaira LA, Biglio A, Van den Borre C, Salzano G, Lechien JR, Mommaerts MY, De Riu G. Hybrid implant-supported rehabilitation of severely atrophic jaws using custom-made subperiosteal and conventional endosseous implants: A retrospective case series. J Craniomaxillofac Surg. 2026,54:104548. (First author, Corresponding author).


    296. Salzano G, Scocca V, Vaira LA, Lechien JR, Scarpa A, Troise S, Orabona GD. Prognostic Factors and Survival Outcomes in Parotid Gland Mucoepidermoid Carcinoma: A Systematic Review with Meta-Analysis and Workflow Proposal. Cancers. 2026; 18(7):1146. https://doi.org/10.3390/cancers18071146


    297. Boscolo-Rizzo P, Giudici F, Polesel J, Tagliabue M, Sia E, Rampinelli V, Stellin M, Emanuelli E, Vaira LA, Zucchini S, Golusinski P, Dequanter D, Estomba CC, Maniaci A, Lentini M, De Berardinis R, Szewczyk M, Lechien JR, Piazza C, Nicolai P, Ansarin M, Tirelli G. Recurrences and Survival in Oropharyngeal Squamous Cell Carcinoma According to p16 Status and Extranodal Extension. Otolaryngol Head Neck Surg. 2026 Apr 14. doi: 10.1002/ohn.70234.


    298. Roy M, Vaira LA, Dorocka Bobkowska B. Pterygoid implants, a graftless alternative solution to rehabilitate posterior maxillary atrophy: a retrospective analysis. J Oral Maxillofac Surg Med Pathol. 2026. Doi: 10.1016/j.ajoms.2026.04.005. (corresponding author)


    299. Russo A, Geremia N, Bavaro DF, Seo SK, Laracy J, Mazzitelli M, Marino A, Maraolo AE, Colpani A, Bartoletti M, Cattelan AM, Mussini C, Parisi SG, Vaira LA, Nunnari G, Madeddu G, De Vito A. Comparing large language models for antibiotic prescribing: an updated analysis using the same clinical benchmark. Clin Microbiol Infect. 2026 Apr 16:S1198-743X(26)00196-5. doi: 10.1016/j.cmi.2026.04.012. 


    300. Consorti G, Betti E, Paglianiti M, Catarzi L, Monarchi G, Gilli M, Troise S, Chiesa-Estomba CM, Vaira LA, Cirignaco G. Combined BTX-A and Collagen Membrane in Benign Parotid Enucleation: A Comparative Cohort Study. Craniomaxillofac Trauma Recon. 2026; 19(2):23.


    301. Lechien JR, Chiesa-Estomba CM, Mayo-Yanez M, Iannella G, Barillari MR, Guarino P, Lazzeroni M, Saibene AM, Cammaroto G, Salzano G, Andrianakis A, Hemptinne C, Saussez S, Maniaci A, Vaira LA. Validity and reliability of the total rating of eye, nasal, and dry-mouth (TREND) score. Eur Arch Otorhinolaryngol. 2026 Apr 23. doi: 10.1007/s00405-026-10216-w. 


    302. Mierzejewska ŻA, Antonowicz B, Woźniak Ł, Lechien JR, Vaira LA, Dziełak S, Borys J. A Redox Amplification Interface Linking Mitochondrial Dysfunction, Immune-Derived Oxidants, and Biomaterial Electrochemistry in Chronic Inflammation. Int J Mol Sci 2026; 27(9):4121.


    303. Chiesa-Estomba CM, Kalfert D, Palacios-Garcia J, Tel A, Vaira LA, Maniaci A et al. Risk of cervical metastasis in primary parotid gland malignancies: A Yo-IFOS Multicenter Retrospective Longitudinal Study. Head Neck. 2026 May 19. doi: 10.1002/hed.70320. 


    304. Mierzejewska ZA, Borys J, Wozniak Ł, Lechien JR, Vaira LA, Łukaszuk K, Antonowicz B. Biomaterial physicochemical properties govern immune activation and bone regeneration: a titanium-focused design-oriented osteoimmunological framework. Front Immunol. 2026;17:1856086. doi: 10.3389/fimmu.2026.1856086


  • Relazioni a congressi

    XXI Congresso della Società Italiana di Chirurgia Maxillo-Facciale

    Lecce, 12-15 Giugno 2019

    Bone marrow stem cells autograft in TMJ degenerative disorders: a clinical trial.

    Vaira LA, Carta E, De Riu G



    International Congres of Oral and Maxillo Facial Surgery 2018.

    Marrakech, 18-21 Aprile 2018

    Bone marrow stem cells autograft in TMJ degenerative disorders: A clinical trial.

    Vaira LA, Carta E, De Riu G


    XX Congresso della Società Italiana di Chirurgia Maxillo-Facciale

    Napoli, 14-17 Giugno 2017

    Valutazione dell’outcome funzionale delle ricostruzioni dei tessuti molli del cavo orale con lembi locali e microfascilari.

    Vaira LA, Massarelli O, Copelli C, Tarabbia F


    XXVI Congresso della Società Italiana di Microchirurgia

    Torino, 26-28 Novembre 2015

    Primi due casi riportati in letteratura di lembi microvascolari mio-mucosi di guancia basati sul peduncolo facciale.

    Massarelli O, Vaira LA, Gobbi R, Soma D


    XXVI Congresso della Società Italiana di Microchirurgia

    Torino, 26-28 Novembre 2015

    Versatilità del lembo osteomiocutaneo di fibula chimerico nella ricostruzione di difetti cervico-facciali tridimensionali.

    Massarelli O, Vaira LA, Gobbi R, Biglio A


    XVIII Congresso della Società Italiana di Chirurgia Maxillo-Facciale

    Padova, 16-18 Maggio 2013

    La ricostruzione funzionale del cavo orale e dell’orofaringe con lembi mio-mucosi di buccinatore: nostra esperienza su 100 lembi

    Massarelli O, Vaira LA, Gobbi R, Soma D, Tullio A


    II Congresso Nazionale AIOCC

    Modena, 7-9 Maggio 2012

    Valutazione funzionale delle ricostruzioni oro-faringee con lembi miomucosi di buccinatore

    Vaira LA, Massarelli O, Tullio A


    V Congresso di medicina e patologia oro-maxillo-facciale – Il carcinoma del cavo orale: approccio multidisciplinare nel miglioramento della qualità di vita.

    Trieste, 9-10 Marzo 2012

    Valutazione funzionale delle ricostruzioni oro-faringee con lembi miomucosi di buccinatore.

    Vaira LA, Massarelli O, Tullio A


    XXXV Convegno Nazionale di aggiornamento AOOI

    Cagliari, 1-2 Ottobre 2011

    Valutazione funzionale delle ricostruzioni oro-faringee con lembi miomucosi di buccinatore.

    Vaira LA, Massarelli O, Tullio A



  • Corsi

    11-12 Aprile 2018, Pacengo di Lazise, Italia. AOCMF Course – Management of facial trauma. AO Foundation


    16 Luglio 2017, Napoli, Italia. Masterclass “Protesi custom made dell’articolazione temporo-mandibolare: indicazioni, tecnica e risultati” (Prof. Piero Cascone). Società Italiana di Chirurgia Maxillo-Facciale.


    15 Giugno 2017, Napoli, Italia. Masterclass “Indicazione, tecnica e risultati della protesi temporo-mandibolare”. (Prof. Guglielmo Ramieri). Società Italiana di Chirurgia Maxillo-Facciale.


    24, 25 e 26 Gennaio 2017, Nizza, Francia. Corso su cadavere di tecnica chirurgica per l’allestimento di lembi microchirurgici. Società Italiana di Microchirurgia.


    14 e 15 Giugno 2012, Napoli, Italia. Incontri culturali di Chirurgia Maxillo-Facciale – 2° Corso Live Surgery. Società Italiana di Chirurgia Maxillo-Facciale.


    18, 19 e 20 Aprile 2012, Torino, Italia. AO-CMF principle course sul trattamento delle fratture del massiccio facciale. AO Foundation.


    30 Gennaio 2009, Sassari, Italia. Corso di addestramento nella rianimazione cardiopolmonare di base con uso di defibrillatori semiautomatici esterni. Esecutore BLS-D. Università degli Studi di Sassari.